{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T11:46:11Z","timestamp":1770983171777,"version":"3.50.1"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2021,2,17]],"date-time":"2021-02-17T00:00:00Z","timestamp":1613520000000},"content-version":"vor","delay-in-days":297,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,8,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Existing data on the safety of out-of-hours cholecystectomy are conflicting. The aim of this study was to investigate whether out-of-hours cholecystectomy for acute cholecystitis is associated with a higher risk for complications compared with surgery during office hours.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This was a population-based cohort study. The Swedish Gallstone Surgery and Endoscopic Retrograde Cholangiopancreatography Register (GallRiks) was used to investigate the association between out-of-hours cholecystectomy for acute cholecystitis and complications developing within 30 days. Data from patients who underwent cholecystectomy between 2006 and 2017 were collected. Out-of-hours surgery was defined as surgery commencing between 19.00 and 07.00 hours on weekdays, or any time at weekends (Friday 19.00 hours to Monday 07.00 hours). Multivariable logistic regression analysis was used to assess the risk of complications, with time of procedure as independent variable. The proportion of open procedures and proportion of procedures exceeding 120 min were also analysed. Adjustments were made for sex, age, ASA grade, time between admission and surgery, and hospital-specific features.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of 11 153 procedures included, complications occurred within 30 days in 1573 patients (14\u00b71 per cent). The adjusted odds ratio (OR) for complications for out-of-hours versus office-hours surgery was 1\u00b712 (95 per cent c.i. 0\u00b799 to 1\u00b728). The adjusted OR for procedures completed as open surgery was 1\u00b739 (1\u00b725 to 1\u00b754), and that for operating time exceeding 120 min was 0\u00b763 (0\u00b758 to 0\u00b769).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Out-of-hours complications may relate to patient factors and the higher proportion of open procedures.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.11633","type":"journal-article","created":{"date-parts":[[2020,4,26]],"date-time":"2020-04-26T16:35:00Z","timestamp":1587918900000},"page":"1313-1323","source":"Crossref","is-referenced-by-count":7,"title":["Is out-of-hours cholecystectomy for acute cholecystitis associated with complications?"],"prefix":"10.1093","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0037-3988","authenticated-orcid":false,"given":"C","family":"Gustafsson","sequence":"first","affiliation":[{"name":"Department of Clinical Science and Education, Karolinska Institutet S\u00f6dersjukhuset , Sjukhusbacken 10, S-118 83, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Dahlberg","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Education, Karolinska Institutet S\u00f6dersjukhuset , Sjukhusbacken 10, S-118 83, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Sond\u00e9n","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Education, Karolinska Institutet S\u00f6dersjukhuset , Sjukhusbacken 10, S-118 83, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"J\u00e4rnbert-Pettersson","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Education, Karolinska Institutet S\u00f6dersjukhuset , Sjukhusbacken 10, S-118 83, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Sandblom","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Education, Karolinska Institutet S\u00f6dersjukhuset , Sjukhusbacken 10, S-118 83, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,4,26]]},"reference":[{"key":"2022100812524707400_bjs11633-bib-0001","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1016\/j.suc.2008.07.005","article-title":"Laparoscopic cholecystectomy","volume":"88","author":"Litwin","year":"2008","journal-title":"Surg Clin North Am"},{"issue":"6","key":"2022100812524707400_bjs11633-bib-0002","first-page":"CD005440","article-title":"Early versus delayed laparoscopic cholecystectomy for people with acute cholecystitis","author":"Gurusamy","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"2022100812524707400_bjs11633-bib-0003","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1097\/SLA.0b013e3182a1599b","article-title":"Acute cholecystitis: early versus delayed cholecystectomy, a multicenter randomized trial (ACDC study, NCT00447304)","volume":"258","author":"Gutt","year":"2013","journal-title":"Ann Surg"},{"key":"2022100812524707400_bjs11633-bib-0004","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s11605-016-3223-y","article-title":"The sooner, the better? 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