{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T01:48:31Z","timestamp":1776131311147,"version":"3.50.1"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2020,7,3]],"date-time":"2020-07-03T00:00:00Z","timestamp":1593734400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000092","name":"U.S. National Library of Medicine","doi-asserted-by":"publisher","award":["T15LM007092"],"award-info":[{"award-number":["T15LM007092"]}],"id":[{"id":"10.13039\/100000092","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,10,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Patients undergoing surgery for soft tissue sarcoma have high morbidity rates, particularly after preoperative radiation therapy (RT). An enhanced recovery after surgery (ERAS) programme may improve perioperative outcomes in abdominal surgery. This study reported outcomes of an ERAS programme tailored to patients with soft tissue sarcoma.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A prospective ERAS protocol was implemented in 2015 at a high-volume sarcoma centre. Patients treated within the ERAS programme from 2015 to 2018 were case-matched retrospectively with patients treated between 2012 and 2018 without use of the protocol, matched by surgical site, surgeon, sarcoma histology and preoperative RT treatment. Postoperative outcomes, specifically wound complications and duration of hospital stay, were reported.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>In total, 234 patients treated within the ERAS programme were matched with 237 who were not. The ERAS group had lower wound dehiscence rates overall (2 of 234 (0\u00b79 per cent) versus 31 of 237 (13\u00b71 per cent); P &amp;lt; 0\u00b7001), after preoperative RT (0 of 41 versus 11 of 51; P =\u00a00\u00b7004) and after extremity sarcoma surgery (0 of 54 versus 6 of 56; P =\u00a00\u00b7040) compared with the non-ERAS group. Rates of postoperative ileus or obstruction were lower in the ERAS group (21 of 234 (9\u00b79 per cent) versus 40 of 237 (16\u00b79 per cent); P =\u00a00\u00b7016) and in those with retroperitoneal sarcoma (4 of 36 versus 15 of 36; P =\u00a00\u00b7007). Duration of hospital stay was shorter in the ERAS group (median 5 (range 0\u201336) versus 6 (0\u201367) days; P =\u00a00\u00b7003).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Treatment within an ERAS protocol for patients with soft tissue sarcoma was associated with lower morbidity and shorter hospital stay.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1002\/bjs.11758","type":"journal-article","created":{"date-parts":[[2020,7,3]],"date-time":"2020-07-03T12:11:45Z","timestamp":1593778305000},"page":"1667-1672","source":"Crossref","is-referenced-by-count":21,"title":["Enhanced recovery after surgery pathway in patients with soft tissue sarcoma"],"prefix":"10.1093","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7759-0799","authenticated-orcid":false,"given":"H G","family":"Lyu","sequence":"first","affiliation":[{"name":"Department of Surgery, Brigham and Women's Hospital , Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L V","family":"Saadat","sequence":"additional","affiliation":[{"name":"Department of Surgery, Brigham and Women's Hospital , Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M M","family":"Bertagnolli","sequence":"additional","affiliation":[{"name":"Department of Surgery, Brigham and Women's Hospital , Boston, Massachusetts, USA"},{"name":"Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute , Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7466-098X","authenticated-orcid":false,"given":"J","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Surgery, Brigham and Women's Hospital , Boston, Massachusetts, USA"},{"name":"Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute , Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E H","family":"Baldini","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Brigham and Women's Hospital , Boston, Massachusetts, USA"},{"name":"Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute , Boston, Massachusetts, USA"},{"name":"Dana-Farber Cancer Institute, Harvard Medical School , Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Stopfkuchen-Evans","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Brigham and Women's Hospital , Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Bleday","sequence":"additional","affiliation":[{"name":"Department of Surgery, Brigham and Women's Hospital , Boston, Massachusetts, USA"},{"name":"Dana-Farber Cancer Institute, Harvard Medical School , Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C P","family":"Raut","sequence":"additional","affiliation":[{"name":"Department of Surgery, Brigham and Women's Hospital , Boston, Massachusetts, USA"},{"name":"Department of Radiation Oncology, Brigham and Women's Hospital , Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,7,3]]},"reference":[{"key":"2022100812565670000_bjs11758-bib-0001","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1001\/jamasurg.2016.4952","article-title":"Enhanced recovery after surgery: a review","volume":"152","author":"Ljungqvist","year":"2017","journal-title":"JAMA Surg"},{"key":"2022100812565670000_bjs11758-bib-0002","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1002\/jpen.1417","article-title":"Implementation of an enhanced recovery after surgery program can change nutrition care practice: a multicenter experience in elective 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