{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T23:33:56Z","timestamp":1770507236506,"version":"3.49.0"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[1974,11,1]],"date-time":"1974-11-01T00:00:00Z","timestamp":152496000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Statens L\u00e6gevidenskabelige Forskningr\u00e5d","award":["512-2508"],"award-info":[{"award-number":["512-2508"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1974,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The role of the vagus in the gastrin response to a steak meal was investigated in patients with duodenal ulcer. Thirty patients were studied before and after vagal denervation of the entire stomach (selective vagotomy and s pyloroplasty). Basal and stimulated gastrin concentrations in serum, as determined by radio-immunoassay, were higher postoperatively (87 pre-\/III postopera-tively (basal)and 2431341 (peak) pglml). Thirty other patients were studied before and after denervation of the gastric body (highly selective vagotomy). Bnsnl and stimulated gastrin concentrations were also higher postoperatively in these patients (94\/133 and 277\/343 pg\/ml respectively). The differences between the two groups were insignificant. Between individuals, gastrin responses varied markedly, but pre- and postoperative responses were positively related within the same subject. No differences were observed between patients with \u2018positive\u2019 or \u2018negative\u2019 Hollander responses to insulin. In 6 subjects studied 2 and 14 weeks postoperatively no difference was apparent between the two studies.<\/jats:p>\n               <jats:p>It is concluded that antral branches of the vagi play only a minor role, if any, in the gastrin response to food.<\/jats:p>","DOI":"10.1002\/bjs.1800611106","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T11:56:27Z","timestamp":1172836587000},"page":"884-888","source":"Crossref","is-referenced-by-count":28,"title":["Gastrin response to food in duodenal ulcer patients before and after selective or highly selective vagotomy"],"prefix":"10.1093","volume":"61","author":[{"given":"F","family":"Stadil","sequence":"first","affiliation":[{"name":"Department of Surgical Gastroenterology C, Rigshospitalet , Copenhagen,","place":["Denmark"]},{"name":"Department of Clinical Chemistry, Bispebjerg Hospital , Copenhagen,","place":["Denmark"]},{"name":"Department of Surgical Gastroenterology A, Bispebjerg Hospital , Copenhagen,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J F","family":"Rehfeld","sequence":"additional","affiliation":[{"name":"Department of Surgical Gastroenterology C, Rigshospitalet , Copenhagen,","place":["Denmark"]},{"name":"Department of Clinical Chemistry, Bispebjerg Hospital , Copenhagen,","place":["Denmark"]},{"name":"Department of Surgical Gastroenterology A, Bispebjerg Hospital , Copenhagen,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P M","family":"Christiansen","sequence":"additional","affiliation":[{"name":"Department of Surgical Gastroenterology C, Rigshospitalet , Copenhagen,","place":["Denmark"]},{"name":"Department of Clinical Chemistry, Bispebjerg Hospital , Copenhagen,","place":["Denmark"]},{"name":"Department of Surgical Gastroenterology A, Bispebjerg Hospital , Copenhagen,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O","family":"Kronborg","sequence":"additional","affiliation":[{"name":"Department of Surgical Gastroenterology C, Rigshospitalet , Copenhagen,","place":["Denmark"]},{"name":"Department of Clinical Chemistry, Bispebjerg Hospital , Copenhagen,","place":["Denmark"]},{"name":"Department of Surgical Gastroenterology A, Bispebjerg Hospital , Copenhagen,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1974,11,1]]},"reference":[{"key":"2024092709342360700_bib1","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/S0016-5085(19)33704-7","article-title":"Selective vagotomy of the parietal cell mass preserving innervation of the undrained antrum","volume":"59","author":"Amdrup","year":"1970","journal-title":"Gastroenterology"},{"key":"2024092709342360700_bib2","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1136\/gut.14.4.293","article-title":"Effect of proximal gastric vagotomy on gastric acid secretion and plasma gastrin","volume":"14","author":"Clark","year":"1973","journal-title":"Gut"},{"key":"2024092709342360700_bib3","first-page":"A 169","article-title":"Evidence for an antral-oxyntic reflex for acid secretion","volume":"64","author":"Debas","year":"1974","journal-title":"Gastroenterology"},{"key":"2024092709342360700_bib4","first-page":"835","volume-title":"Handbook of Physiology","author":"Grossman","year":"1967"},{"key":"2024092709342360700_bib5","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0300-5089(21)00030-4","article-title":"Immunoassay studies in peptic ulcer","volume":"2","author":"Hansky","year":"1973","journal-title":"Clin. Gastroenterol."},{"key":"2024092709342360700_bib6","first-page":"607","article-title":"The insulin test for the presence of intact nerve fibers after vagal operations for peptic ulcer","volume":"7","author":"Hollander","year":"1946","journal-title":"Gastroenterology"},{"key":"2024092709342360700_bib7","first-page":"324","article-title":"Gastrin response to selective and parietal cell vagotomies","volume":"38","author":"Jaffe","year":"1972","journal-title":"Surg. Forum"},{"key":"2024092709342360700_bib8","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/bjs.1800570414","article-title":"Highly selective vagotomy without a drainage procedure in the treatment of duodenal ulcer","volume":"57","author":"Johnston","year":"1970","journal-title":"Br. J. Surg."},{"key":"2024092709342360700_bib9","volume-title":"An Evaluation of the Insulin Test","author":"Kronborg","year":"1972"},{"key":"2024092709342360700_bib10","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1080\/00365521.1973.12096753","article-title":"Gastrins in serum. A review of gastrin radioimmunoanalysis and the discovery of gastrin heterogeneity in serum","volume":"8","author":"Rehfeld","year":"1973","journal-title":"Scand. J. Gastroenterol."},{"key":"2024092709342360700_bib11","doi-asserted-by":"crossref","first-page":"221","DOI":"10.3109\/00365517209081114","article-title":"Production and evaluation of antibodies to gastrin for radioimmunoassay","volume":"30","author":"Rehfeld","year":"1972","journal-title":"Scand. J. Clin. Lub. Invest."},{"key":"2024092709342360700_bib12","first-page":"443","article-title":"Individual variation in secretory capacity of gastric acid to stimulation with solid food and with histamine","volume":"32","author":"Rune","year":"1967","journal-title":"Clin. Sci."},{"key":"2024092709342360700_bib13","volume-title":"Non-parametric Statistics for the Behavioral Sciences","author":"Siegel","year":"1956"},{"key":"2024092709342360700_bib14","first-page":"611","article-title":"Intragastric pressure\/ volume relationship before and after vagotomy","volume":"136","author":"Stadaas","year":"1970","journal-title":"Acta Chir. Scand."},{"key":"2024092709342360700_bib15","doi-asserted-by":"crossref","first-page":"361","DOI":"10.3109\/00365517209080271","article-title":"Preparation of 125I-labelled synthetic human gastrin I for radioimmunoassay","volume":"30","author":"Stadil","year":"1972","journal-title":"Scand. J. Clin. Lab. 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