{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T09:46:02Z","timestamp":1764841562180},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[1975,5,1]],"date-time":"1975-05-01T00:00:00Z","timestamp":168134400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1975,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>One hundred and ninety-six members of 15 families with Gardner's syndrome were investigated to determine the type of skin cyst that is part of this syndrome. These were shown to be epidermoid cysts and not pilar cysts or steatocystoma multiplex. They were solitary or multiple and seldom large and disfiguring. The skin cysts often occurred before the intestinal polyps were detectable. The presence of epidermoid cysts in children should be an indication for sigmoidoscopy when the child reaches the age of 14 years, and at 3-yearly intervals thereafter up to the age of 30 years, whether or not there is a family history of polyposis coli.<\/jats:p>\n               <jats:p>At present it is not possible to say if Gardner's syndrome is the same as, or different from, familial polyposis. Until all patients with colonic polyps have a full clinical examination, looking for skin cysts and osteomas, X-rays of the skull and long bones to detect osteomas and dental X-rays for abnormalities of the teeth this question will remain unanswered.<\/jats:p>","DOI":"10.1002\/bjs.1800620515","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T12:25:40Z","timestamp":1172838340000},"page":"387-393","source":"Crossref","is-referenced-by-count":69,"title":["Epidermoid cysts, polyposis coli and Gardner's syndrome"],"prefix":"10.1093","volume":"62","author":[{"given":"Barbara","family":"Leppard","sequence":"first","affiliation":[{"name":"St Mark's Hospital , London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H J R","family":"Bussey","sequence":"additional","affiliation":[{"name":"St Mark's Hospital , London"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1975,5,1]]},"reference":[{"key":"2024092619375754800_bib1","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1007\/BF02238116","article-title":"Gardner's syndrome. A revisit to a previously reported family","volume":"15","author":"Coli","year":"1970","journal-title":"Am. J. Dig. Dis."},{"key":"2024092619375754800_bib2","first-page":"165","article-title":"Two cases of disseminated polyps of rectum","volume":"33","author":"Cripps","year":"1882","journal-title":"Trans. Path. Soc. Lond."},{"key":"2024092619375754800_bib3","first-page":"241","article-title":"The hereditary factor in polyposis intestini, or multiple adenomata","volume":"5","author":"Dukes","year":"1930","journal-title":"Cancer Rev."},{"key":"2024092619375754800_bib4","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0022-3476(68)80340-3","article-title":"The Gardner syndrome: need for early diagnosis","volume":"72","author":"Duncan","year":"1968","journal-title":"J. Pediatr."},{"key":"2024092619375754800_bib5","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/0030-4220(62)90004-X","article-title":"Gardner's syndrome (intestinal polyposis, osteomas, sebaceous cysts) and a new dental discovery","volume":"15","author":"Fader","year":"1962","journal-title":"Oral Surg."},{"key":"2024092619375754800_bib6","first-page":"167","article-title":"A genetic and clinical study of intestinal polyposis, a predisposing factor for carcinoma of the colon and rectum","volume":"3","author":"Gardner","year":"1951","journal-title":"Am. J. Hum. Genet."},{"key":"2024092619375754800_bib7","first-page":"376","article-title":"Follow up study of a family group exhibiting dominant inheritance for a syndrome including intestinal polyps, osteomas, fibromas and epidermal cysts","volume":"14","author":"Gardner","year":"1962","journal-title":"Am. J. Hum. Genet."},{"key":"2024092619375754800_bib8","first-page":"1","article-title":"Gardner's syndrome re-evaluated after twenty years","volume":"46","author":"Gardner","year":"1969","journal-title":"Proc. Utah Acad. Sci."},{"key":"2024092619375754800_bib9","first-page":"31","article-title":"Hereditary pattern for multiple osteomas in a family group","volume":"4","author":"Gardner","year":"1952","journal-title":"Am. J. Hum. Genet."},{"key":"2024092619375754800_bib10","first-page":"139","article-title":"Multiple cutaneous and subcutaneous lesions occurring simultaneously with hereditary polyposis and osteomatosis","volume":"5","author":"Gardner","year":"1953","journal-title":"Am. J. Hum. Genet."},{"key":"2024092619375754800_bib11","first-page":"41","article-title":"Cancer of the lower digestive tract in one family group","volume":"2","author":"Gardner","year":"1950","journal-title":"Am. J. Hum. Genet."},{"key":"2024092619375754800_bib12","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1136\/bmj.1.3983.960","article-title":"Hereditary sebaceous cysts","volume":"1","author":"Ingram","year":"1937","journal-title":"Br. Med. J."},{"year":"1975","author":"Leppard","key":"2024092619375754800_bib13"},{"key":"2024092619375754800_bib14","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1002\/bjs.1800570816","article-title":"The occurrence of desmoids in patients with familial polyposis coli","volume":"57","author":"McAdam","year":"1970","journal-title":"Br. J. Surg."},{"key":"2024092619375754800_bib15","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1001\/jama.1962.03050420047012","article-title":"Genetic factors in intestinal polyposis","volume":"182","author":"McKusick","year":"1962","journal-title":"JAMA"},{"key":"2024092619375754800_bib16","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1002\/bjs.18004116917","article-title":"The association of familial polyposis of the colon with multiple sebaceous cysts","volume":"41","author":"Oldfield","year":"1954","journal-title":"Br. J. Surg."},{"key":"2024092619375754800_bib17","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1136\/gut.11.4.323","article-title":"Familial polyposis coli associated with extracolonic abnormalities","volume":"11","author":"Parks","year":"1970","journal-title":"Gut"},{"key":"2024092619375754800_bib18","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/BF02616741","article-title":"Familial multiple polyposis: research tool for investigating the etiology of carcinoma of the colon?","volume":"11","author":"Smith","year":"1968","journal-title":"Dis. Colon Rectum"},{"key":"2024092619375754800_bib19","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/0002-9610(68)90032-9","article-title":"Natural history of Gardner's syndrome","volume":"115","author":"Thomas","year":"1968","journal-title":"Am. J. Surg."},{"key":"2024092619375754800_bib20","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1001\/archderm.1964.01600010026007","article-title":"Gardner's syndrome","volume":"90","author":"Weary","year":"1964","journal-title":"Arch. Dermatol."}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.1800620515","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/62\/5\/387\/59360212\/bjs1800620515.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/62\/5\/387\/59360212\/bjs1800620515.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T19:38:11Z","timestamp":1727379491000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/62\/5\/387\/6189985"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1975,5,1]]},"references-count":20,"journal-issue":{"issue":"5","published-online":{"date-parts":[[1975,5,1]]},"published-print":{"date-parts":[[1975,5,1]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.1800620515","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"type":"print","value":"0007-1323"},{"type":"electronic","value":"1365-2168"}],"subject":[],"published-other":{"date-parts":[[1975,5]]},"published":{"date-parts":[[1975,5,1]]}}}