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Clinical assessment of the presence of abdominal disease is unreliable. Exploratory laparotomy with splenectomy, multiple lymph node biopsy and liver biopsy will reveal that preoperative assessment of the extent of the disease is inaccurate in 30 per cent of cases. The information obtained prevents relapses from undiagnosed abdominal disease and ensures that inappropriate radiotherapeutic treatment is not given to patients with disseminated disease.<\/jats:p>","DOI":"10.1002\/bjs.1800621102","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T12:16:24Z","timestamp":1172837784000},"page":"853-862","source":"Crossref","is-referenced-by-count":6,"title":["The role of surgery in the management of Hodgkin's disease"],"prefix":"10.1093","volume":"62","author":[{"given":"Miles","family":"Irving","sequence":"first","affiliation":[{"name":"Department of Surgery, University of Manchester"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1975,11,1]]},"reference":[{"key":"2024092618522530500_bib1","first-page":"1860","article-title":"Reports of the Committee on Hodgkin's Disease Staging Classifications","volume":"31","author":"Carbone","year":"1971","journal-title":"Cancer Res."},{"key":"2024092618522530500_bib2","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1056\/NEJM196706012762203","article-title":"Hazards of overwhelming infection after splenectomy in childhood","volume":"276","author":"Eraklis","year":"1967","journal-title":"New Engl. 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