{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T01:33:25Z","timestamp":1759541605833,"version":"3.27.0"},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[1977,12,1]],"date-time":"1977-12-01T00:00:00Z","timestamp":249782400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1977,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Seventeen patients have completed a double-blind crossover study of hydrotalcite against placebo in the treatment of bile vomiting after surgery for peptic ulcer. Overall there was no significant difference between the two treatments, with 9 patients improving on hydrotalcite and 5 on placebo. The original operation had been performed less than 3 years before the study in 9 patients; in this subgroup there was an improvement on hydrotalcite treatment in 8 patients but in only 1 on placebo. These differences are statistically significant (P &amp;lt; 0\u00b7005). Nausea, vomiting, heartburn and epigastric tenderness were improved although gastritis and endoscopic changes were not affected. It appears that hydrotalcite can help palliate symptoms of bile vomiting occurring soon after surgery for peptic ulcer.<\/jats:p>","DOI":"10.1002\/bjs.1800641204","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T13:33:10Z","timestamp":1172842390000},"page":"849-850","source":"Crossref","is-referenced-by-count":3,"title":["Hydrotalcite in the treatment of bile vomiting"],"prefix":"10.1093","volume":"64","author":[{"given":"A M","family":"Hoare","sequence":"first","affiliation":[{"name":"Queen Elizabeth Hospital and General Hospital , Birmingham"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"McLeish","sequence":"additional","affiliation":[{"name":"Queen Elizabeth Hospital and General Hospital , Birmingham"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Thompson","sequence":"additional","affiliation":[{"name":"Queen Elizabeth Hospital and General Hospital , Birmingham"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Alexander-Williams","sequence":"additional","affiliation":[{"name":"Queen Elizabeth Hospital and General Hospital , Birmingham"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1977,12,1]]},"reference":[{"key":"2024101718091763100_bib1","first-page":"933","article-title":"Postoperative alkali reflux gastritis","volume":"138","author":"Bushkin","year":"1974","journal-title":"Surg. 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Surg."},{"key":"2024101718091763100_bib5","first-page":"1011","article-title":"Hydrogen ion, pepsin and bile acid binding properties of hydrotalcite","volume":"49","author":"Mendelsohn","year":"1975","journal-title":"S. Afr. Med. J."},{"key":"2024101718091763100_bib6","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/0002-9610(75)90172-5","article-title":"Postoperative reflux gastritis","volume":"129","author":"Van Heerden","year":"1975","journal-title":"Am. J. Surg."}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.1800641204","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/64\/12\/849\/59834817\/bjs1800641204.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/64\/12\/849\/59834817\/bjs1800641204.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,17]],"date-time":"2024-10-17T18:37:36Z","timestamp":1729190256000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/64\/12\/849\/6193607"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,12,1]]},"references-count":6,"journal-issue":{"issue":"12","published-online":{"date-parts":[[1977,12,1]]},"published-print":{"date-parts":[[1977,12,1]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.1800641204","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"type":"print","value":"0007-1323"},{"type":"electronic","value":"1365-2168"}],"subject":[],"published-other":{"date-parts":[[1977,12]]},"published":{"date-parts":[[1977,12,1]]}}}