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All were shown to be in negative nitrogen balance and to have a compromised nonspecific cellular immune response. Correction of protein-calorie malnutrition and the achievement of positive nitrogen balance were associated with an increase in absolute lymphocyte and T lymphocyte numbers and a significant increase in lymphocyte response to PHA. The improvement in immunological reactivity occurred without any attempt at therapeutic reduction in tumour bulk.<\/jats:p>","DOI":"10.1002\/bjs.1800650710","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T16:34:32Z","timestamp":1172853272000},"page":"480-482","source":"Crossref","is-referenced-by-count":15,"title":["Diminished cellular immunity due to impaired nutrition in oesophageal carcinoma"],"prefix":"10.1093","volume":"65","author":[{"given":"A A","family":"Haffejee","sequence":"first","affiliation":[{"name":"Department of Surgery, University of Natal , Durban, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I B","family":"Angorn","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Natal , Durban, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P P","family":"Brain","sequence":"additional","affiliation":[{"name":"Institute of Immunology , Prince Street, Durban"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Duursma","sequence":"additional","affiliation":[{"name":"Institute of Immunology , Prince Street, Durban"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L W","family":"Baker","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Natal , Durban, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1978,7,1]]},"reference":[{"key":"2024092619544412500_bib1","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1136\/bmj.3.5716.181","article-title":"Host resistance and survival in carcinoma of the breast: a study of 104 cases of medullary carcinoma in a series of 1411 cases of breast cancer followed for 20 years","volume":"3","author":"Bloom","year":"1970","journal-title":"Br. 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