{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T20:31:25Z","timestamp":1765485085958},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[1978,8,1]],"date-time":"1978-08-01T00:00:00Z","timestamp":270777600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1978,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Gastric aspirates were obtained from 12 healthy volunteers, 49 patients with duodenal ulcer, 14 with gastric ulcer and 35 with gastric carcinoma. The mean total viable bacterial counts in these groups were as follows: volunteers 0, duodenal ulcer 3.8 \u00d7 101, gastric ulcer 6.95 \u00d7 104, carcinoma 1.9 \u00d7 107 organisms\/ml.<\/jats:p>\n               <jats:p>The incidence of wound sepsis in patients without antibiotic cover was: duodenal ulcer 17 per cent, gastric ulcer 38 per cent, carcinoma 56 per cent. Regardless of the underlying pathology, patients with counts greater than 5 \u00d7 106 organisms\/ml in the gastric aspirate had a 93 per cent in incidence of wound sepsis, compared with 16 per cent in patients with counts of less than 5 \u00d7 106 organisms\/ml (P &amp;lt;0.001). In the group with high counts all except one of the wound infections were caused by organisms present in the stomach at the time of operation.<\/jats:p>\n               <jats:p>There was a good correlation in the bacteriology of apirates obtained during preoperative endoscopy compared with operative nasogastric samples (n = 31) both for viable counts (r = 0.93) and for the counts of individual organisms. Therefore, preoperative endoscopy can be used to identify patients who are at risk of developing wound sepsis after gastric surgery.<\/jats:p>","DOI":"10.1002\/bjs.1800650808","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T16:53:24Z","timestamp":1172854404000},"page":"551-554","source":"Crossref","is-referenced-by-count":49,"title":["Prediction of wound sepsis following gastric operations"],"prefix":"10.1093","volume":"65","author":[{"given":"David","family":"Gatehouse","sequence":"first","affiliation":[{"name":"The General Hospital , Birmingham"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frances","family":"Dimock","sequence":"additional","affiliation":[{"name":"The General Hospital , Birmingham"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D W","family":"Burdon","sequence":"additional","affiliation":[{"name":"The General Hospital , Birmingham"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Alexander-Williams","sequence":"additional","affiliation":[{"name":"The General Hospital , Birmingham"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M R B","family":"Keighley","sequence":"additional","affiliation":[{"name":"The General Hospital , Birmingham"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1978,8,1]]},"reference":[{"key":"2024092619542001900_bib1","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1136\/bmj.2.4848.1248","article-title":"The bacterial content of human small intestine disease of the stomach","volume":"2","author":"Cregan","year":"1953","journal-title":"Br. 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