{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T10:06:54Z","timestamp":1768903614036,"version":"3.49.0"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[1978,11,1]],"date-time":"1978-11-01T00:00:00Z","timestamp":278726400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1978,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The results of a randomized, prospective clinicol trial of highly selective vagotomy (HSV) versus truncal vagotomy and pyloroplasty (TVP) in 126 male patients undergoing elective surgery for chronic duodenal ulceration are presented. The operations were performed by surgeons of all grades of experience. At a mean follow-up time of just over 3 years a satisfactory result was obtained in 93 per cent of patients following HSV and 78 per cent of patients following TVP, the difference being probably statistically significant (P&amp;lt;0.05). The incidence of early and late dumping, bile vomiting, flatulence, post-prandial epigastric discomfort and wound infection was statistically significantly less after HSV than after TVP. Three patients have developed a recurrent duodenal ulcer after each type of operation (5.4 per cent). At this early stage HSV has advantages over TVP; it will be interesting to see if these are maintained with the passage of time.<\/jats:p>","DOI":"10.1002\/bjs.1800651109","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T16:24:02Z","timestamp":1172852642000},"page":"793-796","source":"Crossref","is-referenced-by-count":28,"title":["Highly selective vagotomy or truncal vagotomy and pyloroplasty for chronic duodenal ulceration: A randomized, prospective clinical study"],"prefix":"10.1093","volume":"65","author":[{"given":"C J","family":"Stoddard","sequence":"first","affiliation":[{"name":"University Surgical Unit, Royal Infirmary , Sheffield"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J S","family":"Vassilakis","sequence":"additional","affiliation":[{"name":"University Surgical Unit, Royal Infirmary , Sheffield"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H L","family":"Duthie","sequence":"additional","affiliation":[{"name":"University Surgical Unit, Royal Infirmary , Sheffield"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1978,11,1]]},"reference":[{"key":"2024092619573051900_bib1","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/S0016-5085(19)33704-7","article-title":"Selective vagotomy of the parietal cell mass preserving innervation of the undrained antrum","volume":"59","author":"Amdrup","year":"1970","journal-title":"Gastroenterology"},{"key":"2024092619573051900_bib2","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1097\/00000658-197409000-00004","article-title":"Clinical results of parietal cell vagotomy (highly selective vagotomy) 2 to 4 years after operation","volume":"180","author":"Amdrup","year":"1974","journal-title":"Ann. Surg."},{"key":"2024092619573051900_bib3","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1136\/gut.14.4.300","article-title":"The effect of preserving antral innervation and of a pyloroplasty on gastric emptying after vagotomy in men","volume":"14","author":"Clarke","year":"1973","journal-title":"Gut"},{"key":"2024092619573051900_bib4","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1002\/bjs.1800650303","article-title":"Prospective randomised multicentre trial of proximal gastric vagotomy or truncal vagotomy and antrectomy for chronic duodenal ulcer: interim results","volume":"65","author":"Dorricott","year":"1978","journal-title":"Br. J. 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