{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T10:06:36Z","timestamp":1783591596345,"version":"3.55.0"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[1979,4,1]],"date-time":"1979-04-01T00:00:00Z","timestamp":291772800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1979,4,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>A prospective study has been undertaken on 24 patients to establish the relationship between the degree of internal carotid artery stenosis, as estimated by arteriography, and the pulse wave transit time in the carotid artery. The technique involves the simultaneous use of two continuous wave Doppler velocimeters, one on the carotid and one on the supraorbital artery, to measure the flow waves and hence deduce the pulse wave transit times. The measured transit times varied from 17 to 124 ms with a beat-to-beat variation of 11 per cent.<\/jats:p>\n               <jats:p>The absolute transit time in any segment correlated moderately well with the estimated degree of stenosis (r = 0.68, P &amp;lt; 0.001). However, normalization of the transit times, to correct for the effects of blood pressure and age, produced an improved correlation between the variables (r = 0.8, P &amp;lt; 0.001). Normalization was achieved by dividing the common carotid to supraorbital transit time by the shortest transit time found between the common carotid and either the superficial temporal or brachial arteries.<\/jats:p>\n               <jats:p>Significant differences in the normalized transit times were found between arteries that were diametrically stenosed by more than 50 per cent, by between 21 and 50 per cent and by 20 per cent or below. It is concluded that pulse wave transit time measurement can provide a simple and reproducible non-invasive technique for the diagnosis of varying degrees of carotid artery stenosis.<\/jats:p>","DOI":"10.1002\/bjs.1800660415","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T17:26:22Z","timestamp":1172856382000},"page":"265-268","source":"Crossref","is-referenced-by-count":6,"title":["Assessment of carotid artery stenosis using pulse wave transit time"],"prefix":"10.1093","volume":"66","author":[{"given":"M","family":"Horrocks","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering, King's College Hospital Medical School , London SE5"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V C","family":"Roberts","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, King's College Hospital Medical School , London SE5"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L T","family":"Cotton","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, King's College Hospital Medical School , London SE5"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1979,4,1]]},"reference":[{"key":"2024092708214793000_bib1","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1093\/cvr\/11.2.147","article-title":"Screening for carotid junction disease by spectral analysis of Doppler signals","volume":"11","author":"Baskett","year":"1977","journal-title":"Cardiovasc. Res."},{"key":"2024092708214793000_bib2","doi-asserted-by":"crossref","first-page":"143","DOI":"10.3171\/jns.1968.29.2.0143","article-title":"Detection of carotid artery bifurcation stenosis by Doppler ultrasound","volume":"29","author":"Brinker","year":"1968","journal-title":"J. Neurosurg."},{"key":"2024092708214793000_bib3","volume-title":"Screening for the Prevention of Stroke","author":"Brockenbrough","year":"1964"},{"key":"2024092708214793000_bib4","volume-title":"The Mechanics of the Circulation","author":"Caro","year":"1978"},{"key":"2024092708214793000_bib5","first-page":"17P","article-title":"Doppler shift spectra in the assessment of peripheral arteries","volume":"266","author":"Cotton","year":"1976","journal-title":"J. Physiol (Lond.)"},{"key":"2024092708214793000_bib6","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1161\/01.STR.1.3.149","article-title":"Anatomic and haemodynamic correlations in carotid artery stenosis","volume":"1","author":"Deweese","year":"1970","journal-title":"Stroke"},{"key":"2024092708214793000_bib7","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1056\/NEJM197511272932205","article-title":"Evaluation of carotid stenosis by phonoangiography","volume":"293","author":"Duncan","year":"1975","journal-title":"N. Engl. J. Med."},{"key":"2024092708214793000_bib8","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1016\/S0140-6736(54)90544-9","article-title":"Reconstruction of the internal carotid artery in patients with intermittent attacks of hemiplegia","volume":"2","author":"Eastcott","year":"1954","journal-title":"Lancet"},{"key":"2024092708214793000_bib9","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1001\/jama.1968.03140110047010","article-title":"Joint study of extracranial arterial occlusion as a cause of stroke (I)","volume":"203","author":"Fields","year":"1968","journal-title":"JAMA"},{"key":"2024092708214793000_bib10","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1001\/jama.1970.03170120039008","article-title":"Joint study of extracranial arterial occlusion (V)","volume":"211","author":"Fields","year":"1970","journal-title":"JAMA"},{"key":"2024092708214793000_bib11","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1161\/01.STR.7.1.18","article-title":"Non-invasive diagnosis of carotid occlusion by ocular pneumoplethysmography","volume":"7","author":"Gee","year":"1976","journal-title":"Stroke"},{"key":"2024092708214793000_bib12","first-page":"244","article-title":"Ocular pneumoplethysmography in carotid artery disease","volume":"8","author":"Gee","year":"1974","journal-title":"Med. Instrum."},{"key":"2024092708214793000_bib13","first-page":"271","article-title":"Comparison of non-invasive diagnosis techniques in carotid artery occlusive disease","volume":"82","author":"Gross","year":"1977","journal-title":"Surgery"},{"key":"2024092708214793000_bib14","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1148\/90.3.586","article-title":"Evaluation of cerebrovascular disease utilizing a transcutaneous Doppler technique","volume":"90","author":"Grossman","year":"1968","journal-title":"Radiology"},{"key":"2024092708214793000_bib15","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1001\/jama.1968.03140110053011","article-title":"Joint study of extracranial arterial occlusion (II)","volume":"203","author":"Hass","year":"1968","journal-title":"JAMA"},{"key":"2024092708214793000_bib16","first-page":"80","article-title":"Natural history of carotid bifurcation atheroma","volume":"67","author":"Javid","year":"1970","journal-title":"Surgery"},{"key":"2024092708214793000_bib17","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1001\/archsurg.1973.01350160142024","article-title":"Noninvasive detection of evaluation of carotid occlusive disease","volume":"106","author":"Kartchner","year":"1973","journal-title":"Arch. Surg."},{"key":"2024092708214793000_bib18","first-page":"840","article-title":"Noninvasive evaluation and management of the asymptomatic' bruit","volume":"82","author":"Kartchner","year":"1977","journal-title":"Surgery"},{"key":"2024092708214793000_bib19","first-page":"40","volume-title":"Blood Flow Measurement","author":"King","year":"1972"},{"key":"2024092708214793000_bib20","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1177\/000331977302400608","article-title":"Evaluation of patients with cerebrovascular disease using the Doppler ophthalmic test","volume":"24","author":"Machleder","year":"1973","journal-title":"Angiology"},{"key":"2024092708214793000_bib21","doi-asserted-by":"crossref","first-page":"238","DOI":"10.3171\/jns.1969.30.3part1.0238","article-title":"Ophthalmosonometry\u2014an ultrasonic method for assessing carotid blood flow","volume":"30","author":"Maroon","year":"1969","journal-title":"J. Neurosurg."},{"key":"2024092708214793000_bib22","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1148\/92.4.908","article-title":"Radioisotope arteriography: as an adjunct to the brain scan","volume":"92","author":"Maynard","year":"1969","journal-title":"Radiology"},{"key":"2024092708214793000_bib23","first-page":"305","volume-title":"Cardiovascular Application of Ultrasound","author":"Mol","year":"1974"},{"key":"2024092708214793000_bib24","author":"Roberts","year":"1978"},{"key":"2024092708214793000_bib25","first-page":"695","article-title":"The use of velocity wave form analysis in the diagnosis of carotid artery occlusive disease","volume":"82","author":"Rutherford","year":"1977","journal-title":"Surgery"},{"key":"2024092708214793000_bib26","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1001\/archsurg.1975.01360130045009","article-title":"Ophthalmic arterial blood pressures measured by ocular plethysmodynamography","volume":"110","author":"Sand","year":"1975","journal-title":"Arch. Surg."},{"key":"2024092708214793000_bib27","first-page":"160","volume-title":"Proceedings XIth International Conference on Medical and Biological Engineering","author":"Stevens","year":"1976"},{"key":"2024092708214793000_bib28","first-page":"77","article-title":"Management of asymptomatic carotid bruit","volume":"42","author":"Thompson","year":"1976","journal-title":"Ann. Surg."},{"key":"2024092708214793000_bib29","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1161\/01.STR.2.2.105","article-title":"The detection of carotid artery obstruction: a correlation with arteriography","volume":"2","author":"Wise","year":"1971","journal-title":"Stroke"},{"key":"2024092708214793000_bib30","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1088\/0031-9155\/2\/4\/301","article-title":"Oscillatory flow in arteries. Reflections of the pulse wave at junction and rigid inserts","volume":"2","author":"Womersley","year":"1958","journal-title":"Phys. Med. Biol."},{"key":"2024092708214793000_bib31","first-page":"124","article-title":"Diagnostic value of thermography in extracranial carotid occlusive disease","volume":"90","author":"Wood","year":"1965","journal-title":"Trans. Am. Neurol. Assoc."}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.1800660415","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/66\/4\/265\/59364640\/bjs1800660415.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/66\/4\/265\/59364640\/bjs1800660415.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T08:21:59Z","timestamp":1727425319000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/66\/4\/265\/6180337"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,4,1]]},"references-count":31,"journal-issue":{"issue":"4","published-online":{"date-parts":[[1979,4,1]]},"published-print":{"date-parts":[[1979,4,1]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.1800660415","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"value":"0007-1323","type":"print"},{"value":"1365-2168","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1979,4]]},"published":{"date-parts":[[1979,4,1]]}}}