{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:21:09Z","timestamp":1760188869304},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[1979,9,1]],"date-time":"1979-09-01T00:00:00Z","timestamp":304992000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1979,9,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>A prospective randomized matched pair study was designed to test the efficacy of the peritoneovenous (LeVeen) shunt as a treatment for massive cirrhotic ascites compared with traditional medical therapy. Patients who failed to lose weight while on a low salt diet and fluids restricted to 1000 ml daily were placed in the study group. Weight loss, decrease in abdominal girth and diuresis were significantly greater (P &amp;lt; 0\u00b701) for surgical patients than for their medically treated counterparts. The surgical technique is simple, quick and inexpensive. The surgical patients outlived their matched partners in 12 of 14 pairs where a definitive comparison was possible (P &amp;lt; 0\u00b702). The median stay in hospital after randomization was shortened from 32 days with medical therapy to 15 days for those undergoing the shunt operation. Those treated medically experienced a significant rise in mean blood urea nitrogen and K+ (P &amp;lt; 0\u00b702). Patients with alcoholic hepatitis, hyperbilirubinaemia (bilirubin &amp;gt; 154 m\u0308mol\/l), peritoneal sepsis, severe coagulopathy and those who had recently bled from oesophageal varices are poor risks for the surgical procedure.<\/jats:p>","DOI":"10.1002\/bjs.1800660924","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T18:26:34Z","timestamp":1172859994000},"page":"667-670","source":"Crossref","is-referenced-by-count":34,"title":["Randomized prospective matched pair study comparing peritoneovenous shunt and conventional therapy in massive ascites"],"prefix":"10.1093","volume":"66","author":[{"given":"Simon","family":"Wapnick","sequence":"first","affiliation":[{"name":"Departments of Surgery and Gastrointestinal Section (Medicine), VA Hospital and Downstate Medical Center, SUNY , Brooklyn, New York 11209"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saul J","family":"Grosberg","sequence":"additional","affiliation":[{"name":"Departments of Surgery and Gastrointestinal Section (Medicine), VA Hospital and Downstate Medical Center, SUNY , Brooklyn, New York 11209"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark I","family":"Evans","sequence":"additional","affiliation":[{"name":"Departments of Surgery and Gastrointestinal Section (Medicine), VA Hospital and Downstate Medical Center, SUNY , Brooklyn, New York 11209"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1979,9,1]]},"reference":[{"key":"2024092709410707500_bib1","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/S0016-5085(19)34229-5","article-title":"Intravenous therapy of massive ascites in patients with cirrhosis: II. 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