{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:20:55Z","timestamp":1760188855874,"version":"3.37.3"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[1981,11,1]],"date-time":"1981-11-01T00:00:00Z","timestamp":373420800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]},{"name":"North West Thames Regional Authority Locally Organized Research Scheme"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1981,11,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Radionuclide biliary scanning with 99Tcm-labelled HIDA was performed in 36 patients with acute pancreatitis within 3 days of admission. Twenty had a non-visualized gallbladder on scanning and all were subsequently shown by cholecystography (n = 16) andlor operation (n = 16) to have underlying gallstones; 5 of the 16 cholecystograms revealed a \u2018functioning\u2019 gallbladder. Sixteen patients had normal HIDA scans with gallbladder visualization, and subsequently all were shown by cholecystography (n = 15) or operation (n = 1) to have a normal biliary tree; 15 of these had an alcoholic background. In the differentiation of gallstone from non-gallstone pancreatitis, biliary scanning was completely accurate and a better discriminant than the liver function profile or the clinical features, the latter being valueless.<\/jats:p>\n               <jats:p>Whether or not the gallbladder is visualized on biliary scanning depends on the presence or absence of cystic duct obstruction, a fact confirmed in two other groups: in 53 patients with acute cholecystitis and non-visualized gallbladders on scanning, 52 were subsequently shown to have \u2018non-functioning\u2019 gallbladders by oral cholecystography (1 having stones in a functioning gallbladder), whereas 9 other patients with normal biliary scans, all had \u2018functioning\u2019 gallbladders on oral cholecystography.<\/jats:p>\n               <jats:p>Thus, acute gallstone pancreatitis appears to be accompanied in the early stages by occlusion of the cystic duct, though this is a transient phenomenon in about one-third of the patients. The cause of this occlusion may be oedema in some cases but its relationship to the pathogenesis of acute pancreatitis is unclear.<\/jats:p>","DOI":"10.1002\/bjs.1800681105","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T20:16:49Z","timestamp":1172866609000},"page":"766-770","source":"Crossref","is-referenced-by-count":19,"title":["Radionuclide biliary scanning in acute pancreatitis"],"prefix":"10.1093","volume":"68","author":[{"given":"Geoffrey","family":"Glazer","sequence":"first","affiliation":[{"name":"St Mary's Hospital , Praed Street, London W2 1NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Murphy","sequence":"additional","affiliation":[{"name":"St Mary's Hospital , Praed Street, London W2 1NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerald S","family":"Clayden","sequence":"additional","affiliation":[{"name":"St Mary's Hospital , Praed Street, London W2 1NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosemary G","family":"Lawrence","sequence":"additional","affiliation":[{"name":"St Mary's Hospital , Praed Street, London W2 1NY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oscar","family":"Craig","sequence":"additional","affiliation":[{"name":"St Mary's Hospital , Praed Street, London W2 1NY"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1981,11,1]]},"reference":[{"key":"2024092711265680900_bib1","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1056\/NEJM188207131070203","article-title":"Pancreatic apoplexy with a report of two cases","volume":"107","author":"Prince","year":"1882","journal-title":"Boston Med. 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