{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:31:59Z","timestamp":1791329519022,"version":"4.3.1"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[1982,10,1]],"date-time":"1982-10-01T00:00:00Z","timestamp":402278400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Wellcome Surgical Fellowship"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1982,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The effect of 32 split ileostomies on 29 patients with severe symptomatic perianal Crohn's disease is reported. The perianal disease improved or healed after 23 (72 per cent) split ileostomies, although it relapsed in 2 patients while diverted and in 6 after closure of the split ileostomy. Seven of 12 rectovaginal fistulas healed initially but only remained healed in those patients without rectal involvement with disease. At the time of review 6 patients have normal bowel continuity, 8 have had proctocolectomies and 15 are still defunctioned. Split ileostomy should be considered as an initial step in the management of intractable perianal disease.<\/jats:p>","DOI":"10.1002\/bjs.1800691017","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T21:32:15Z","timestamp":1172871135000},"page":"608-610","source":"Crossref","is-referenced-by-count":83,"title":["The effect of split ileostomy on perianal Crohn's disease"],"prefix":"10.1093","volume":"69","author":[{"given":"P H","family":"Harper","sequence":"first","affiliation":[{"name":"Nuffield Department of Surgery, John Radcliffe Hospital , Oxford"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M G W","family":"Kettlewell","sequence":"additional","affiliation":[{"name":"Nuffield Department of Surgery, John Radcliffe Hospital , Oxford"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E C G","family":"Lee","sequence":"additional","affiliation":[{"name":"Nuffield Department of Surgery, John Radcliffe Hospital , Oxford"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1982,10,1]]},"reference":[{"key":"2024092713143382400_bib1","first-page":"32","article-title":"Perianal lesions in Crohn's disease","volume":"17","author":"Fielding","year":"1972","journal-title":"J. R. Coll. Surg. Edinb."},{"key":"2024092713143382400_bib2","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1007\/BF02590945","article-title":"Fistula-in-ano: management of Crohn's fistula","volume":"19","author":"Alexander-Williams","year":"1976","journal-title":"Dis. Colon Rectum"},{"key":"2024092713143382400_bib3","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1056\/NEJM198005083021906","article-title":"Surgical management of Crohn's colitis","volume":"302","author":"Block","year":"1980","journal-title":"N. Engl. J. Med."},{"key":"2024092713143382400_bib4","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1007\/BF02587272","article-title":"Symposium: Crohn's disease: anal lesions","volume":"18","author":"Lockhart-Mummery","year":"1975","journal-title":"Dis. Colon Rectum"},{"key":"2024092713143382400_bib5","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1002\/bjs.1800680802","article-title":"Anal fistulas in Crohn's disease","volume":"68","author":"Marks","year":"1981","journal-title":"Br. J. Surg."},{"key":"2024092713143382400_bib6","article-title":"Split ileostomy and ileo-colostomy for Crohn's disease of the colon and ulcerative colitis: a 20 year survey","volume-title":"Gut","author":"Harper"},{"key":"2024092713143382400_bib7","first-page":"94","article-title":"Split ileostomy in the treatment of Crohn's disease of the colon","volume":"56","author":"Lee","year":"1975","journal-title":"Ann. R. Coll. Surg. Engl."},{"key":"2024092713143382400_bib8","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1136\/gut.1.2.87","article-title":"Crohn's disease (regional enteritis) of the large intestine and its distinction from ulcerative colitis","volume":"1","author":"Lockhart-Mummery","year":"1960","journal-title":"Gut"},{"key":"2024092713143382400_bib9","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1136\/gut.5.6.493","article-title":"Crohn's disease of the large intestine","volume":"5","author":"Lockhart-Mummery","year":"1964","journal-title":"Gut"},{"key":"2024092713143382400_bib10","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/0002-9610(80)90301-3","article-title":"Anorectal Crohn's disease: definitive surgery for fistulas and recurrent abscesses","volume":"139","author":"Sohn","year":"1980","journal-title":"Am. J. Surg."},{"key":"2024092713143382400_bib11","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1177\/014107687807100904","article-title":"Surgical pathology and management of anorectal Crohn's disease","volume":"71","author":"Hughes","year":"1978","journal-title":"J. R. Soc. Med."},{"key":"2024092713143382400_bib12","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1097\/00000658-197101000-00013","article-title":"Ileostomy for granulomatous colitis","volume":"173","author":"Aufses","year":"1971","journal-title":"Ann. Surg."},{"key":"2024092713143382400_bib13","first-page":"239","volume-title":"The Management of Crohn's Disease","author":"Alexander-Williams","year":"1976"},{"key":"2024092713143382400_bib14","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1136\/gut.21.6.525","article-title":"Occurrence and outcome after primary treatment of anal fistulae in Crohn's disease","volume":"21","author":"Hellers","year":"1980","journal-title":"Gut"},{"key":"2024092713143382400_bib15","first-page":"224","volume-title":"The Management of Crohn's Disease","author":"Weterman","year":"1976"},{"key":"2024092713143382400_bib16","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1001\/archsurg.1971.01350080224035","article-title":"Diverting ileostomy or colostomy in the management of Crohn's disease of the colon","volume":"103","author":"McIlrath","year":"1971","journal-title":"Arch. Surg."},{"key":"2024092713143382400_bib17","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1097\/00000658-198002000-00006","article-title":"Loop ileostomy in the management of Crohn's colitis in the debilitated patient","volume":"191","author":"Zelas","year":"1980","journal-title":"Ann. Surg."},{"key":"2024092713143382400_bib18","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1136\/gut.12.1.11","article-title":"The effects of diversion of intestinal contents on the progress of Crohn's disease of the large bowel","volume":"12","author":"Burman","year":"1971","journal-title":"Gut"},{"key":"2024092713143382400_bib19","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1136\/gut.7.5.448","article-title":"Experience in the treatment of Crohn's disease of the large intestine","volume":"7","author":"Jones","year":"1966","journal-title":"Gut"},{"key":"2024092713143382400_bib20","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1001\/archsurg.1976.01360300023003","article-title":"Anal lesions complicating Crohn's disease","volume":"111","author":"Homan","year":"1976","journal-title":"Arch. Surg."},{"key":"2024092713143382400_bib21","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1007\/BF02590971","article-title":"Inflammatory disease of the bowel: indications for surgery","volume":"19","author":"Oberhelman","year":"1976","journal-title":"Dis. Colon Rectum"},{"key":"2024092713143382400_bib22","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1080\/00365521.1976.12097130","article-title":"Crohn's disease of the distal large bowel","volume":"11","author":"Ritchie","year":"1976","journal-title":"Scand. J. Gastroenterol."},{"key":"2024092713143382400_bib23","first-page":"141","article-title":"Loop ileostomy and colostomy for faceal diversion","volume":"54","author":"Alexander-Williams","year":"1974","journal-title":"Ann. R. Coll. Surg. Engl."},{"key":"2024092713143382400_bib24","first-page":"245","volume-title":"Surgery of the Anus, Rectum and Colon","author":"Goligher","year":"1975","edition":"3rd"},{"key":"2024092713143382400_bib25","first-page":"216","volume-title":"The Management of Crohn's Disease","author":"Oberhelman","year":"1976"},{"key":"2024092713143382400_bib26","first-page":"20","article-title":"Acquired fistulae between the intestine and vagina","volume":"46","author":"Hudson","year":"1970","journal-title":"Ann. R. Coll. Surg. Engl."},{"key":"2024092713143382400_bib27","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1007\/BF02586761","article-title":"Rectovaginal fistula in Crohn's disease","volume":"22","author":"Tuxen","year":"1979","journal-title":"Dis. Colon Rectum"}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.1800691017","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/69\/10\/608\/59372001\/bjs1800691017.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/69\/10\/608\/59372001\/bjs1800691017.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T13:14:47Z","timestamp":1727442887000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/69\/10\/608\/6185955"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,10,1]]},"references-count":27,"journal-issue":{"issue":"10","published-online":{"date-parts":[[1982,10,1]]},"published-print":{"date-parts":[[1982,10,1]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.1800691017","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"value":"0007-1323","type":"print"},{"value":"1365-2168","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1982,10]]},"published":{"date-parts":[[1982,10,1]]}}}