{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T21:51:47Z","timestamp":1767649907609},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[1983,10,1]],"date-time":"1983-10-01T00:00:00Z","timestamp":433814400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1983,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The importance of the direct perforating veins of the lower leg in the aetiology of venous ulceration is supported by the results of a 6-year study of 77 patients with 109 ulcerated legs. Incompetent perforating veins were demonstrated by examination and Doppler ultrasound, and confirmed at operation, in 108 legs. Subfascial ligation of these veins, with stripping of incompetent saphenous veins when necessary, was followed by elastic compression stockings in 44 legs (40 per cent) in which deep vein incompetence was demonstrated by non-invasive methods and phlebography. Some 91 ulcers (84\u00b73 per cent) remain healed (76 per cent &amp;gt; 3-year follow up). Eight patients with rheumatoid arthritis in addition to venous incompetence had a 75 per cent failure rate. If these patients are excluded, 88 (92 per cent) of 96 ulcerated legs remain healed. It is submitted that these results support the argument for the importance of perforating vein incompetence in the aetiology of venous ulceration. They also suggest that a more optimistic attitude towards treatment is justified.<\/jats:p>","DOI":"10.1002\/bjs.1800701016","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T22:51:10Z","timestamp":1172875870000},"page":"623-627","source":"Crossref","is-referenced-by-count":119,"title":["The effective management of venous ulceration"],"prefix":"10.1093","volume":"70","author":[{"given":"D","family":"Negus","sequence":"first","affiliation":[{"name":"Lewisham Hospital , London SE13 6LH"},{"name":"Hither Green Hospital , London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Friedgood","sequence":"additional","affiliation":[{"name":"Lewisham Hospital , London SE13 6LH"},{"name":"Hither Green Hospital , London"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1983,10,1]]},"reference":[{"key":"2024092715093957100_bib1","first-page":"48","article-title":"Chronic venous insufficiency of the lower extremity","volume":"49","author":"Cranley","year":"1961","journal-title":"Surgery"},{"key":"2024092715093957100_bib2","first-page":"269","article-title":"Venous ulcers of the lower limb","volume":"128","author":"Hansson","year":"1964","journal-title":"Acta Chir. 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