{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T01:50:29Z","timestamp":1790128229564,"version":"4.0.1"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[1984,1,1]],"date-time":"1984-01-01T00:00:00Z","timestamp":441763200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1984,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>During a 2-year period the diagnostic value of 99mTc-labelled-plasmin test was evaluated in 63 patients admitted with clinical signs of deep vein thrombosis (DVT). In comparison with a conventional phlebography the diagnostic sensitivity and specificity of the plasmin test was 0\u00b797 and 0\u00b755, respectively. The predictive value in positive cases was 0\u00b779 and in negative 0\u00b792. The sensitivity was highest for thrombosis in the calf and popliteal regions, while the specificity was higher for thrombosis in the femoral veins. It is concluded that the 99mTc-labelled-plasmin test is suitable for DVT-screening in groups of high-risk patients and is simple and rapid. In positive cases the DVT diagnosis must be verified by phlebography.<\/jats:p>","DOI":"10.1002\/bjs.1800710121","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T00:10:31Z","timestamp":1172880631000},"page":"65-66","source":"Crossref","is-referenced-by-count":9,"title":["Deep vein thrombosis detection by 99mTc-plasmin test and phlebography"],"prefix":"10.1093","volume":"71","author":[{"given":"S E","family":"Husted","sequence":"first","affiliation":[{"name":"Medical Department I, Surgical Department I, Radiological Department, County Hospital of Aarhus, Nuclear Medical Department, Municipal Hospital of Aarhus , DK-8000 Aarhus C,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H Kr\u00e1mmer","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Medical Department I, Surgical Department I, Radiological Department, County Hospital of Aarhus, Nuclear Medical Department, Municipal Hospital of Aarhus , DK-8000 Aarhus C,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Krusell","sequence":"additional","affiliation":[{"name":"Medical Department I, Surgical Department I, Radiological Department, County Hospital of Aarhus, Nuclear Medical Department, Municipal Hospital of Aarhus , DK-8000 Aarhus C,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Fasting","sequence":"additional","affiliation":[{"name":"Medical Department I, Surgical Department I, Radiological Department, County Hospital of Aarhus, Nuclear Medical Department, Municipal Hospital of Aarhus , DK-8000 Aarhus C,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B Ostergaard","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Medical Department I, Surgical Department I, Radiological Department, County Hospital of Aarhus, Nuclear Medical Department, Municipal Hospital of Aarhus , DK-8000 Aarhus C,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J Bruun","family":"Pedersen","sequence":"additional","affiliation":[{"name":"Medical Department I, Surgical Department I, Radiological Department, County Hospital of Aarhus, Nuclear Medical Department, Municipal Hospital of Aarhus , DK-8000 Aarhus C,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Dalgaard","sequence":"additional","affiliation":[{"name":"Medical Department I, Surgical Department I, Radiological Department, County Hospital of Aarhus, Nuclear Medical Department, Municipal Hospital of Aarhus , DK-8000 Aarhus C,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H Hvid","family":"Hansen","sequence":"additional","affiliation":[{"name":"Medical Department I, Surgical Department I, Radiological Department, County Hospital of Aarhus, Nuclear Medical Department, Municipal Hospital of Aarhus , DK-8000 Aarhus C,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1984,1,1]]},"reference":[{"key":"2024092715224067000_bib1","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0033-0620(75)80017-X","article-title":"Natural history of pulmonary embolism","volume":"17","author":"Dalen","year":"1975","journal-title":"Prog Cardiovasc Dis"},{"key":"2024092715224067000_bib2","volume-title":"On the diagnosis of deep vein thrombosis","author":"Olsson","year":"1979"},{"key":"2024092715224067000_bib3","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/S0009-9260(78)80207-4","article-title":"Local complication of ascending phlebography","volume":"29","author":"Berge","year":"1978","journal-title":"Clin Radiol"},{"key":"2024092715224067000_bib4","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1093\/oxfordjournals.bmb.a071487","article-title":"Diagnosis of deep-vein thrombosis","volume":"34","author":"Browse","year":"1978","journal-title":"Br Med Bull"},{"key":"2024092715224067000_bib5","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1097\/00006231-198202000-00007","article-title":"Tc-99m plasmin for rapid detection of deep vein thrombosis","volume":"3","author":"Olsson","year":"1982","journal-title":"Nucl Med Com"},{"key":"2024092715224067000_bib6","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0020-708X(77)90163-6","article-title":"Labeling plasmin with technetium-99m for scintigraphic localization of thrombi","volume":"28","author":"Persson","year":"1977","journal-title":"Int J Appl Radiat Isot"},{"key":"2024092715224067000_bib7","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1001\/archsurg.1972.04180020014004","article-title":"Roentgen diagnosis of venous thrombosis in the leg","volume":"104","author":"Rabinov","year":"1972","journal-title":"Arch Surg"},{"key":"2024092715224067000_bib8","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1056\/NEJM198106253042602","article-title":"Cost effectiveness of clinical diagnosis, venography, and noninvasive testing in patients with symptomatic deep-vein thrombosis","volume":"304","author":"Hull","year":"1981","journal-title":"N Engl J Med"},{"key":"2024092715224067000_bib9","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1097\/00000658-198112000-00011","article-title":"The role of two non-invasive tests in deep venous thrombosis","volume":"194","author":"Hanel","year":"1981","journal-title":"Ann Surg"},{"key":"2024092715224067000_bib10","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1259\/0007-1285-53-631-673","article-title":"Technetium-99m-plasmin: A new test for the detection of deep vein thrombosis","volume":"53","author":"Deacon","year":"1980","journal-title":"Br J Radiol"},{"key":"2024092715224067000_bib11","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.0954-6820.1982.tb01903.x","article-title":"Diagnosis of deep venous thrombosis by phlebography and 99mTc-plasmin","volume":"211","author":"Edenbrandt","year":"1982","journal-title":"Acta Med Scand"},{"key":"2024092715224067000_bib12","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/j.0954-6820.1982.tb01963.x","article-title":"Diagnosis of deep vein thrombosis with 99mTc-plasmin","volume":"211","author":"Adolfsson","year":"1982","journal-title":"Acta Med Scand"},{"key":"2024092715224067000_bib13","doi-asserted-by":"crossref","first-page":"677","DOI":"10.3109\/00365517909108874","article-title":"A modified 125I fibrinogen technique for thrombus detection in the whole leg","volume":"39","author":"Olsson","year":"1979","journal-title":"Scand J Clin Lab Invest"},{"key":"2024092715224067000_bib14","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1161\/01.CIR.64.3.622","article-title":"Clinical validity of a negative venogram in patients with clinically suspected venous thrombosis","volume":"64","author":"Hull","year":"1981","journal-title":"Circulation"}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.1800710121","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/71\/1\/65\/59376862\/bjs1800710121.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/71\/1\/65\/59376862\/bjs1800710121.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T15:22:53Z","timestamp":1727450573000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/71\/1\/65\/6181654"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,1,1]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[1984,1,1]]},"published-print":{"date-parts":[[1984,1,1]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.1800710121","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"value":"0007-1323","type":"print"},{"value":"1365-2168","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1984,1]]},"published":{"date-parts":[[1984,1,1]]}}}