{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T05:15:24Z","timestamp":1777439724443,"version":"3.51.4"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[1984,7,1]],"date-time":"1984-07-01T00:00:00Z","timestamp":457488000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1984,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A preliminary laboratory study has been undertaken using dogs, in which porous Dacron arterial prostheses have been seeded with autologous peritoneal mesothelial cells before implantation into the arterial system. These cells were harvested from omentum by collagenase digestion and were introduced into the graft at the time of preclotting. Examination of the grafts by scanning and transmission electron microscopy one month after insertion showed no organized cellular lining in the control graft. In three seeded grafts there was a lining of mesothelial cells which extended over the whole surface of the grafts up to 1 cm from the suture lines. Selected areas of the grafts have been analysed morphometrically. In the seeded grafts there is a cellular layer which on average covers 94 per cent of the luminal surface. These results suggest that mesothelial cells, which both secrete prostacyclin and possess fibrinolytic activity, present a possible alternative to endothelium as a cellular lining for prosthetic grafts.<\/jats:p>","DOI":"10.1002\/bjs.1800710704","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T00:53:41Z","timestamp":1172883221000},"page":"492-494","source":"Crossref","is-referenced-by-count":40,"title":["Seeding Dacron arterial prostheses with peritoneal mesothelial cells: A preliminary morphological study"],"prefix":"10.1093","volume":"71","author":[{"given":"J M F","family":"Clarke","sequence":"first","affiliation":[{"name":"Departments of Surgery, Histopathology and Oncology, The Middlesex Hospital Medical School , Mortimer Street, London,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R M","family":"Pittilo","sequence":"additional","affiliation":[{"name":"Departments of Surgery, Histopathology and Oncology, The Middlesex Hospital Medical School , Mortimer Street, London,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L J","family":"Nicholson","sequence":"additional","affiliation":[{"name":"Departments of Surgery, Histopathology and Oncology, The Middlesex Hospital Medical School , Mortimer Street, London,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Woolf","sequence":"additional","affiliation":[{"name":"Departments of Surgery, Histopathology and Oncology, The Middlesex Hospital Medical School , Mortimer Street, London,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Marston","sequence":"additional","affiliation":[{"name":"Departments of Surgery, Histopathology and Oncology, The Middlesex Hospital Medical School , Mortimer Street, London,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1984,7,1]]},"reference":[{"key":"2024092716420298900_bib1","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1097\/00000658-197201000-00018","article-title":"Healing of arterial prostheses in man: its incompleteness","volume":"175","author":"Berger","year":"1972","journal-title":"Ann Surg"},{"key":"2024092716420298900_bib2","first-page":"498","article-title":"A single staged technique for seeding vascular grafts with autogenous endothelium","volume":"84","author":"Herring","year":"1978","journal-title":"Surgery"},{"key":"2024092716420298900_bib3","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1001\/archsurg.1980.01380080025005","article-title":"Endothelial seeding of prosthetic vascular grafts","volume":"115","author":"Graham","year":"1980","journal-title":"Arch Surg"},{"key":"2024092716420298900_bib4","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1055\/s-0038-1661019","article-title":"A study of the possible role of mesothelium as a surface for flowing blood","volume":"51","author":"Clarke","year":"1984","journal-title":"Thrombos Haemostas"},{"key":"2024092716420298900_bib5","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/S0090-6980(79)80062-3","article-title":"Biosynthesis of prostacyclin (PGI2) and 12, 1 hydroxy 5, 8, 10, 14 eichosatetraenoic acid (HETE) by pericardium, pleura and peritoneum and aorta of rabbit","volume":"18","author":"Herman","year":"1979","journal-title":"Prostaglandins"},{"key":"2024092716420298900_bib6","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1097\/00000658-197811000-00005","article-title":"The preclotting of porous arterial prostheses","volume":"188","author":"Yates","year":"1978","journal-title":"Ann Surg"},{"key":"2024092716420298900_bib7","first-page":"12","article-title":"Surface thrombogenicity of arterial prostheses","volume":"136","author":"Yates","year":"1973","journal-title":"Surg Gynecol Obstet"},{"key":"2024092716420298900_bib8","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1097\/00000658-197907000-00019","article-title":"Seeding arterial prosthesis with vascular endothelium. 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