{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:21:39Z","timestamp":1740126099848,"version":"3.37.3"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[1984,10,1]],"date-time":"1984-10-01T00:00:00Z","timestamp":465436800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Wessex Regional Health Authority"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1984,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The effect of chronic progressive distal large bowel obstruction on intestinal blood flow was studied in 12 mini-pigs. Blood flow was measured by the techniques of xenon133 clearance and intracardiac injections of radiolabelled microspheres. Intestinal blood flow was increased in the left colon and ileum but decreased in the caecum. Blood was shunted from the mucosa to the muscle layers. The results suggest that primary anastomosis of the obstructed left colon is not contraindicated by haemodynamic considerations.<\/jats:p>","DOI":"10.1002\/bjs.1800711020","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T00:09:56Z","timestamp":1172880596000},"page":"795-798","source":"Crossref","is-referenced-by-count":4,"title":["Changes in intestinal blood flow during the development of chronic large bowel obstruction"],"prefix":"10.1093","volume":"71","author":[{"given":"J E","family":"Coxon","sequence":"first","affiliation":[{"name":"University Surgical Unit, Southampton General Hospital , Tremona Road, Southampton SO9 4XY,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"Dickson","sequence":"additional","affiliation":[{"name":"University Surgical Unit, Southampton General Hospital , Tremona Road, Southampton SO9 4XY,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Taylor","sequence":"additional","affiliation":[{"name":"University Surgical Unit, Southampton General Hospital , Tremona Road, Southampton SO9 4XY,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1984,10,1]]},"reference":[{"key":"2024092715164174400_bib1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1002\/bjs.1800610105","article-title":"Survival after primary and after staged resection for large bowel obstruction caused by cancer","volume":"61","author":"Fielding","year":"1974","journal-title":"Br J Surg"},{"key":"2024092715164174400_bib2","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1097\/00000658-197106010-00017","article-title":"Obstruction and perforation in colorectal cancer","volume":"173","author":"Glenn","year":"1971","journal-title":"Ann Surg"},{"key":"2024092715164174400_bib3","first-page":"541","article-title":"Treatment of obstructing cancer of the colon and rectum","volume":"141","author":"Clark","year":"1975","journal-title":"Surg Gynecol Obstet"},{"key":"2024092715164174400_bib4","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1002\/bjs.1800641015","article-title":"The treatment of colonic cancer presenting with intestinal obstruction","volume":"64","author":"Irvin","year":"1977","journal-title":"Br J Surg"},{"key":"2024092715164174400_bib5","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/bjs.18004519109","article-title":"The treatment of acute obstruction or perforation with carcinoma of the colon and rectum","volume":"45","author":"Goligher","year":"1957","journal-title":"Br J Surg"},{"key":"2024092715164174400_bib6","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/0002-9610(76)90417-7","article-title":"Mortality and prognosis of obstructing carcinoma of the large bowel","volume":"131","author":"Dutton","year":"1976","journal-title":"Am J Surg"},{"key":"2024092715164174400_bib7","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/0002-9610(74)90028-2","article-title":"Recent experiences in the management of cancer of the colon and rectum","volume":"127","author":"Welch","year":"1974","journal-title":"Am J Surg"},{"key":"2024092715164174400_bib8","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/0002-9610(69)90308-0","article-title":"Pathophysiological effects of bowel distension on intestinal blood flow","volume":"117","author":"Boley","year":"1969","journal-title":"Am J Surg"},{"key":"2024092715164174400_bib9","first-page":"536","article-title":"Studies on small intestinal obstruction. 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