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Over a 4 year period 190 patients with 209 asymptomatic stenoses of the internal carotid artery were prospectively studied by means of Doppler ultrasound in combination with real time spectral analysis to determine the natural history of asymptomatic carotid stenosis. We report a cumulative stroke-free survival of 97 per cent at 3 years and we therefore question the merit of prophylactic endarterectomy in the management of asymptomatic carotid disease.<\/jats:p>","DOI":"10.1002\/bjs.1800720424","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T04:44:48Z","timestamp":1172897088000},"page":"313-314","source":"Crossref","is-referenced-by-count":16,"title":["Asymptomatic carotid stenosis: Is prophylactic endarterectomy justifiable?"],"prefix":"10.1093","volume":"72","author":[{"given":"Mary P","family":"Colgan","sequence":"first","affiliation":[{"name":"Department of Vascular Surgery, St James's Hospital , PO Box 580, Dublin 8,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wiley","family":"Kingston","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, St James's Hospital , PO Box 580, Dublin 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