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All patients were screened with the 125I-labelled fibrinogen uptake test, and thromboembolism was verified by ascending phlebography and\/or perfusion\/ventilation lung scintigraphy. In the group of patients receiving low-dose heparin treatment (5000 units twice daily subcutaneously) 12 per cent developed thromboembolic complications. In the other group, where low-dose heparin treatment was supplemented with graded compression stockings only 2 per cent developed thromboembolism. It is concluded that the combination of low-dose heparin and the use of graded compression stockings is superior to heparin alone in preventing thromboembolism following major abdominal surgery.<\/jats:p>","DOI":"10.1002\/bjs.1800720726","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T06:26:49Z","timestamp":1172903209000},"page":"579-581","source":"Crossref","is-referenced-by-count":69,"title":["Heparin with and without graded compression stockings in the prevention of thromboembolic complications of major abdominal surgery: A randomized trial"],"prefix":"10.1093","volume":"72","author":[{"given":"P","family":"Wille-J\u00f8rgensen","sequence":"first","affiliation":[{"name":"Departments of Surgical Gastroenterology and Clinical Physiology, Herlev Hospital, University of Copenhagen ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Thorup","sequence":"additional","affiliation":[{"name":"Departments of Surgical Gastroenterology and Clinical Physiology, Herlev Hospital, University of Copenhagen ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Fischer","sequence":"additional","affiliation":[{"name":"Departments of Surgical Gastroenterology and Clinical Physiology, Herlev Hospital, University of Copenhagen ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Holst-Christensen","sequence":"additional","affiliation":[{"name":"Departments of Surgical Gastroenterology and Clinical Physiology, Herlev Hospital, University of Copenhagen ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Flamsholt","sequence":"additional","affiliation":[{"name":"Departments of Surgical Gastroenterology and Clinical Physiology, Herlev Hospital, University of Copenhagen ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1985,7,1]]},"reference":[{"key":"2024092717383467000_bib1","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/S0308-2261(21)00237-X","article-title":"Prevention of venous thromboembolism","volume":"10","author":"Kakkar","year":"1981","journal-title":"Clin Haematol"},{"key":"2024092717383467000_bib2","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1001\/archsurg.1983.01390080034010","article-title":"Heparin with and without dihydroergotamine in the prevention of thromboembolic complications of major abdominal surgery","volume":"118","author":"Wille-J\u00f8rgensen","year":"1983","journal-title":"Arch Surg"},{"key":"2024092717383467000_bib3","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1002\/bjs.1800700311","article-title":"The use of graduated compression stockings in the prevention of post-operative deep venous thrombosis","volume":"70","author":"Allan","year":"1983","journal-title":"Br J Surg"},{"key":"2024092717383467000_bib4","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1002\/bjs.1800670710","article-title":"Low dose heparin and compression stockings in the prevention of postoperative venous thrombosis","volume":"67","author":"T\u00f6rngren","year":"1980","journal-title":"Br J Surg"},{"key":"2024092717383467000_bib5","first-page":"172","volume-title":"Documenta Geigy Scientific Tables","author":"Diem","year":"1970","edition":"7th"},{"key":"2024092717383467000_bib6","doi-asserted-by":"crossref","first-page":"677","DOI":"10.3109\/00365517909108874","article-title":"A modified 125I-fibrinogen technique for thrombus detection in the whole leg","volume":"39","author":"Olsson","year":"1979","journal-title":"Scand J Clin Lab Invest"},{"key":"2024092717383467000_bib7","first-page":"45","article-title":"International Multicenter trial. 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