{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T12:04:28Z","timestamp":1792152268662,"version":"4.4.0"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[1986,3,1]],"date-time":"1986-03-01T00:00:00Z","timestamp":510019200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1986,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Forty-nine patients undergoing surgery for familial polyposis coli (FPC) over a twenty year period are presented. Forty-three patients underwent total colectomy with ileorectal anastomosis (TC + IRA) and five patients subsequently developed a rectal carcinoma. The incidence of rectal carcinomafollowing TC + IRA appears to increase with time. There were significant postoperative complications secondary to adhesive obstruction and desmoid tumour recurrence. Upper gastrointestinal pathology has been detected by endoscopy in only one of nine patients, but the importance of upper gastrointestinal pathology is now appreciated. The problem of screening a widely distributed and closely knit community has been considerable. TC + IRA remains the operation of choice for the majority of patients with FPC, but a total colectomy with ieal reservoir and ileo-anal anastomosis is appropriate in some cases.<\/jats:p>","DOI":"10.1002\/bjs.1800730319","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T06:49:28Z","timestamp":1172904568000},"page":"210-213","source":"Crossref","is-referenced-by-count":10,"title":["Twenty year experience with familial polyposis coli in Cape Town"],"prefix":"10.1093","volume":"73","author":[{"given":"R J","family":"Aitken","sequence":"first","affiliation":[{"name":"Department of Surgery, University of Cape Town Medical School , Observatory 7925, Cape Town,","place":["South Africa"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M S","family":"Elliot","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Cape Town Medical School , Observatory 7925, Cape Town,","place":["South Africa"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Torrington","sequence":"additional","affiliation":[{"name":"Medical Research Council , Tygerberg 7500, Cape Town,","place":["South Africa"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J H","family":"Louw","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Cape Town Medical School , Observatory 7925, Cape Town,","place":["South Africa"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1986,3,1]]},"reference":[{"key":"2024092718112795800_bib1","volume-title":"Familial Polyposis Coli: Family Studies, Histopathology, Differential Diagnosis and Results of Treatment","author":"Bussey","year":"1975"},{"key":"2024092718112795800_bib2","first-page":"1855","volume-title":"Abdominal Operations","author":"Lockhart-Mummery","year":"1980","edition":"7th"},{"key":"2024092718112795800_bib3","first-page":"399","volume-title":"Surgery of the Anus, Rectum and Colon","author":"Goligher","year":"1984","edition":"5th"},{"key":"2024092718112795800_bib4","first-page":"41","article-title":"Cancer of the lower digestive tract in one family group","volume":"2","author":"Gardner","year":"1950","journal-title":"Am J Hum Genet"},{"key":"2024092718112795800_bib5","first-page":"167","article-title":"Genetic and clinical study of intestinal polyposis; predisposing factors for carcinoma of the colon and rectum","volume":"3","author":"Gardner","year":"1951","journal-title":"Am J Hum Genet"},{"key":"2024092718112795800_bib6","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/S0016-5085(50)80231-7","article-title":"Involvement of the stomach in familial polyposis of the gastrointestinal tract: report of a family","volume":"15","author":"Halstead","year":"1950","journal-title":"Gastroenterology"},{"key":"2024092718112795800_bib7","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1136\/gut.24.4.333","article-title":"Peltokallio. 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