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Normal subjects (n = 20) have a sensory threshold varying from 2 to 7\u00b73 mA being most acute in the region of the anal valves. Sensory awareness also extends into the upper anal canal. Patients with neuropathic incontinence (n = 17) have a sensory deficit (P &amp;lt;0\u00b7002) whilst patients with haemorrhoids (n = 28) have less sensitive mucosa displaced into the upper anal canal (P &amp;lt; 0\u00b70001). Patients with acute fissure-in-ano (n = 10) have lower thresholds of sensation at the site of the fissure and slow transit constipation patients (n = 22) have normal anal sensation. The technique is reproducible and should prove useful in the investigation of anorectal disorders.<\/jats:p>","DOI":"10.1002\/bjs.1800730421","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T06:49:10Z","timestamp":1172904550000},"page":"310-312","source":"Crossref","is-referenced-by-count":157,"title":["New method for assessment of anal sensation in various anorectal disorders"],"prefix":"10.1093","volume":"73","author":[{"given":"A M","family":"Roe","sequence":"first","affiliation":[{"name":"University Department of Surgery, Bristol Royal Infirmary , Bristol BS2 8HW,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D C C","family":"Bartolo","sequence":"additional","affiliation":[{"name":"University Department of Surgery, Bristol Royal Infirmary , Bristol BS2 8HW,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N J","family":"McC. 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