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We describe a minor modification of our initial technique. Patients having segmental splenectomy had a similar postoperative course to those having total splenectomy. Conversion of a segmental to a total splenectomy was required in two cases due to technical faults. No regrowth of the spleen has occurred in up to 4 years of observation. We noted an increased percentage of T lymphocytes with an increased ratio of T helper to T suppressor cells in patients having segmental splenectomy. Our cumulative experience supports adoption and wider evaluation of segmental splenectomy in schistosomiasis.<\/jats:p>","DOI":"10.1002\/bjs.1800730709","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T07:29:45Z","timestamp":1172906985000},"page":"544-547","source":"Crossref","is-referenced-by-count":9,"title":["Clinical and immunological results of segmental splenectomy in schistosomiasis"],"prefix":"10.1093","volume":"73","author":[{"given":"R","family":"Kamel","sequence":"first","affiliation":[{"name":"Liver Research Unit, Ain Shams University Faculty of Medicine ,","place":["Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M A","family":"Dunn","sequence":"additional","affiliation":[{"name":"US Naval Medical Research Unit No. 3 ,","place":["Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R R","family":"Skelly","sequence":"additional","affiliation":[{"name":"US Naval Medical Research Unit No. 3 ,","place":["Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I A","family":"Kamel","sequence":"additional","affiliation":[{"name":"Department of Pathology, Cairo University Faculty of Medicine ; Cairo,","place":["Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M G","family":"Zayed","sequence":"additional","affiliation":[{"name":"Liver Research Unit, Ain Shams University Faculty of Medicine ,","place":["Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Ramadan","sequence":"additional","affiliation":[{"name":"Liver Research Unit, Ain Shams University Faculty of Medicine ,","place":["Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R A","family":"Cahill","sequence":"additional","affiliation":[{"name":"US Naval Medical Research Unit No. 3 ,","place":["Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"el Maharakawy","sequence":"additional","affiliation":[{"name":"Liver Research Unit, Ain Shams University Faculty of Medicine ,","place":["Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Ismail","sequence":"additional","affiliation":[{"name":"Liver Research Unit, Ain Shams University Faculty of Medicine ,","place":["Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Ahmed","sequence":"additional","affiliation":[{"name":"US Naval Medical Research Unit No. 3 ,","place":["Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1986,7,1]]},"reference":[{"key":"2024092718210741500_bib1","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1002\/bjs.1800690605","article-title":"Segmental splenectomy in schistosomiasis","volume":"69","author":"Kamel","year":"1982","journal-title":"Br J Surg"},{"key":"2024092718210741500_bib2","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1001\/archsurg.1979.01370280103015","article-title":"Techniques of splenic conservation","volume":"114","author":"Morganstern","year":"1979","journal-title":"Arch Surg"},{"key":"2024092718210741500_bib3","first-page":"516","article-title":"Anatomy and techniques in segmental splenectomy","volume":"150","author":"Dixon","year":"1980","journal-title":"Surg Gynecol Obstet"},{"key":"2024092718210741500_bib4","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/S0016-5085(76)80557-4","article-title":"Hepatitis B surface antigen carrier state in hepatosplenic schistosomiasis","volume":"71","author":"Lyra","year":"1976","journal-title":"Gastroenterology"},{"key":"2024092718210741500_bib5","doi-asserted-by":"crossref","first-page":"15","DOI":"10.4049\/jimmunol.130.1.15","article-title":"Cell surface phenotype of lymphoid cells from normal mice and mice treated with monoclonal anti-IgD from birth","volume":"130","author":"Skelly","year":"1983","journal-title":"J Immunol"},{"key":"2024092718210741500_bib6","first-page":"232","article-title":"Gastroesophageal decongestion and splenectomy. A method of prevention and treatment of bleeding from esophageal varices associated with bilharzial hepatic fibrosis: preliminary report","volume":"41","author":"Hassab","year":"1964","journal-title":"J Int Coll Surg"},{"key":"2024092718210741500_bib7","doi-asserted-by":"crossref","first-page":"191","DOI":"10.4049\/jimmunol.132.1.191","article-title":"Alterations in immunoglobulin synthesis by peripheral blood mononuclear cells from splenectomized patients with and without splenic regrowth","volume":"132","author":"Drew","year":"1984","journal-title":"J Immunol"},{"key":"2024092718210741500_bib8","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1136\/bmj.287.6408.1829","article-title":"Role of spleen in immune response to polyvalent pneumococcal vaccine","volume":"287","author":"DiPadova","year":"1983","journal-title":"Br Med J"},{"key":"2024092718210741500_bib9","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1600-0609.1983.tb02141.x","article-title":"The cellular immune response after splenectomy in humans. 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