{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T21:12:05Z","timestamp":1760217125900},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[1986,11,1]],"date-time":"1986-11-01T00:00:00Z","timestamp":531187200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1986,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Transcutaneous oxygen (P \u00a0tcO2) measurements were made on 46 patients with severe ischaemia of the lower limbs and on 17 age-matched controls. Values breathing air, 100 per cent oxygen and the rate of change of P \u00a0tcO2 breathing oxygen were recorded. Of 29 below knee amputations there were 4 failures; 16 had P \u00a0tcO2 values &amp;lt; 35 mmHg, but 12 of the 16 healed. When the rate of change of P \u00a0tcO2 during oxygen inhalation was greater than 9 mmHg\/min all below knee amputations healed; all 4 failures were found to have values &amp;lt; 9 mmHg\/min while only one patient with a value of &amp;lt; 9 mmHg\/min healed a below knee amputation. This study shows that low P \u00a0tcO2 values are a poor indication of healing potential. A more reliable index of skin viability is provided by the dynamic measurement PtcO2 changes during oxygen inhalation. The addition of an oxygen inhalation test, when making P \u00a0tcO2 measurements, greatly enhances the applicability of the technique in the assessment of the oxygen supply to the skin.<\/jats:p>","DOI":"10.1002\/bjs.1800731108","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T06:36:09Z","timestamp":1172903769000},"page":"882-885","source":"Crossref","is-referenced-by-count":32,"title":["Oxygen inhalation induced changes in the skin as measured by transcutaneous oxymetry"],"prefix":"10.1093","volume":"73","author":[{"given":"P T","family":"McCollum","sequence":"first","affiliation":[{"name":"Vascular Laboratory, Ninewells Hospital , Dundee DD1 9SY,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V A","family":"Spence","sequence":"additional","affiliation":[{"name":"Vascular Laboratory, Ninewells Hospital , Dundee DD1 9SY,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W F","family":"Walker","sequence":"additional","affiliation":[{"name":"Vascular Laboratory, Ninewells Hospital , Dundee DD1 9SY,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1986,11,1]]},"reference":[{"key":"2024100215113244500_bib1","first-page":"121","volume-title":"Oxygen Measurements in Biology and Medicine","author":"Huch","year":"1975"},{"key":"2024100215113244500_bib2","first-page":"525","article-title":"Transcutaneous oxygen tension measurements in peripheral vascular disease","volume":"150","author":"Matsen","year":"1980","journal-title":"Surg Gynecol Obstet"},{"key":"2024100215113244500_bib3","first-page":"156","article-title":"Transcutaneous PO2 measurements in health and peripheral arterial occlusive disease","volume":"91","author":"Franzeck","year":"1982","journal-title":"Surgery"},{"key":"2024100215113244500_bib4","first-page":"582","article-title":"Transcutaneous partial oxygen pressure assessment of the ischaemic lower limb","volume":"156","author":"Mustapha","year":"1983","journal-title":"Surg Gynecol Obstet"},{"key":"2024100215113244500_bib5","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1302\/0301-620X.65B1.6822606","article-title":"Measurement of transcutaneous oxygen pressure in normal and ischaemic skin","volume":"65","author":"Dowd","year":"1983","journal-title":"J Bone J Surg"},{"key":"2024100215113244500_bib6","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1002\/bjs.1800710320","article-title":"Prediction of amputation wound healing: The role of transcutaneous pO2 assessment","volume":"71","author":"Ratliff","year":"1984","journal-title":"Br J Surg"},{"key":"2024100215113244500_bib7","first-page":"331","volume-title":"Diagnostic Techniques and Assessment Procedures in Vascular Surgery","author":"Spence","year":"1985"},{"key":"2024100215113244500_bib8","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1093\/cvr\/18.3.140","article-title":"Tissue oxygen tension in normal and ischaemic human skin","volume":"18","author":"Spence","year":"1984","journal-title":"Cardiovasc Res"},{"key":"2024100215113244500_bib9","first-page":"123","volume-title":"Advances in Biology of Skin","author":"Urbach","year":"1961"},{"key":"2024100215113244500_bib10","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0034-5687(67)90020-5","article-title":"The systemic oxygen supply to the surface of human skin","volume":"3","author":"Evans","year":"1967","journal-title":"Resp Physiol"},{"key":"2024100215113244500_bib11","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1042\/cs0600499","article-title":"Dependence of transcutaneous oxygen tension on local arteriovenous pressure gradient in normal subject","volume":"60","author":"Wyss","year":"1981","journal-title":"Clin Sci"},{"key":"2024100215113244500_bib12","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1002\/bjs.1800720423","article-title":"Circumferential skin blood flow measurements in the ischaemic limb","volume":"72","author":"McCollum","year":"1985","journal-title":"Br J Surg"},{"key":"2024100215113244500_bib13","doi-asserted-by":"crossref","first-page":"67","DOI":"10.3109\/03093648409145351","article-title":"Assessment of tissue viability in relation to the selection of amputation level","volume":"8","author":"Spence","year":"1984","journal-title":"Prosth Orthot Int"},{"key":"2024100215113244500_bib14","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1097\/00000658-198408000-00007","article-title":"The use of transcutaneous oxygen tension measurements in the diagnosis of peripheral vascular insufficiency","volume":"200","author":"Byrne","year":"1984","journal-title":"Ann Surg"},{"key":"2024100215113244500_bib15","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1088\/0143-0815\/6\/2\/005","article-title":"The effect of the transcutaneous electrode on the variability of dermal oxygen tension changes","volume":"6","author":"Spence","year":"1985","journal-title":"Clin Phys Physiol Meas"},{"key":"2024100215113244500_bib16","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1177\/000331978103201205","article-title":"Quantitative evaluation of skin circulation in ischaemic legs by transcutaneous measurement of oxygen tension","volume":"32","author":"Ohgi","year":"1981","journal-title":"Angiology"},{"key":"2024100215113244500_bib17","first-page":"62","article-title":"Int Soc Cardiovasc Surg (Proc of 32nd meeting, Atlanta)","volume-title":"Oxygen inhalation induced transcutaneous PO2 changes as a predictor of amputation level","author":"Harward","year":"1984"}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.1800731108","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/73\/11\/882\/59495710\/bjs1800731108.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/73\/11\/882\/59495710\/bjs1800731108.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T15:47:52Z","timestamp":1727884072000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/73\/11\/882\/6182461"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,11,1]]},"references-count":17,"journal-issue":{"issue":"11","published-online":{"date-parts":[[1986,11,1]]},"published-print":{"date-parts":[[1986,11,1]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.1800731108","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"type":"print","value":"0007-1323"},{"type":"electronic","value":"1365-2168"}],"subject":[],"published-other":{"date-parts":[[1986,11]]},"published":{"date-parts":[[1986,11,1]]}}}