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After lateral internal sphincterotomy the pressure dropped by 50 per cent to normal levels and the fissures healed with no change in pressure over 12 months. Ten patients also had normal anal pressures and were asymptomatic 4\u20136 years after internal sphincterotomy. Adequate internal sphincterotomy appears to reduce permanently anal canal pressure, suggesting that abnormal activity in the sphincter contributes to the development of a fissure.<\/jats:p>","DOI":"10.1002\/bjs.1800731123","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T06:36:09Z","timestamp":1172903769000},"page":"915-916","source":"Crossref","is-referenced-by-count":52,"title":["Internal sphincterotomy for chronic anal fissure: Long term effects on anal pressure"],"prefix":"10.1093","volume":"73","author":[{"given":"N L","family":"Chowcat","sequence":"first","affiliation":[{"name":"Department of Surgery, Faculty of Clinical Sciences, University College London, Rayne Institute , 5 University Street, London WC1E 6JJ,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J G C","family":"Araujo","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Clinical Sciences, University College London, Rayne Institute , 5 University Street, London WC1E 6JJ,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P B","family":"Boulos","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Clinical Sciences, University College London, Rayne Institute , 5 University Street, London WC1E 6JJ,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1986,11,1]]},"reference":[{"key":"2024100215103521600_bib1","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/S0016-5085(19)32882-3","article-title":"Internal anal sphincter derangement with anal fissures","volume":"67","author":"Nothmann","year":"1974","journal-title":"Gastroenterology"},{"key":"2024100215103521600_bib2","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1002\/bjs.1800510514","article-title":"The functional importance of the internal anal 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