{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T21:48:21Z","timestamp":1767649701211},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[1987,1,1]],"date-time":"1987-01-01T00:00:00Z","timestamp":536457600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1987,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The classical Whipple procedure for chronic pancreatitis has been associated with significant long term postoperative morbidity. The pylorus-preserving procedure of Longmire has reduced but not eliminated the long-term morbidity. Preservation of the whole duodenum with total pancreatectomy has been introduced for the treatment of patients with end-stage chronic pancreatitis after favourable experience with this procedure in infants for nesidioblastosis. Fourteen patients with chronic pancreatitis have had a total pancreatectomy with preservation of the duodenum and the bile duct. All patients are still alive (median follow-up 9\u00b75 months) and none suffered major complications in the perioperative period. One patient developed a biliary stricture at 3 months, requiring biliary reconstruction. Six of the patients have returned to full-time work; nine require no analgesia. All patients require pancreatic enzyme replacement, and all patients have gained weight postoperatively. Diabetic control is satisfactory with a twice daily insulin regime. Duodenum-preserving total pancreatectomy is feasible in the adult without mortality or high morbidity; early experience suggests that preserving the duodenum improves gastrointestinal function with easier control of the diabetes.<\/jats:p>","DOI":"10.1002\/bjs.1800740112","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T07:54:23Z","timestamp":1172908463000},"page":"35-39","source":"Crossref","is-referenced-by-count":59,"title":["Duodenum-preserving total pancreatectomy for end stage chronic pancreatitis"],"prefix":"10.1093","volume":"74","author":[{"given":"M A","family":"Lambert","sequence":"first","affiliation":[{"name":"Department of Surgery, The Middlesex Hospital , Mortimer Street, London W1N8AA,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I P","family":"Linehan","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Middlesex Hospital , Mortimer Street, London W1N8AA,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R C G","family":"Russell","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Middlesex Hospital , Mortimer Street, London W1N8AA,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1987,1,1]]},"reference":[{"key":"2024092719355112400_bib1","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1097\/00000658-197610000-00002","article-title":"Pancreatectomy for chronic pancreatitis","volume":"184","author":"Frey","year":"1976","journal-title":"Ann Surg"},{"key":"2024092719355112400_bib2","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1097\/00000658-197909000-00006","article-title":"Surgical treatment of chronic pancreatitis","volume":"190","author":"Traverso","year":"1979","journal-title":"Ann Surg"},{"key":"2024092719355112400_bib3","first-page":"623","article-title":"Observations on radical 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