{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T20:01:18Z","timestamp":1791921678129,"version":"4.3.4"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[1987,8,1]],"date-time":"1987-08-01T00:00:00Z","timestamp":554774400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1987,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Case notes of 250 patients (M:F, 1:2\u00b77; age 48\u00b77\u00b116\u00b75 years) in whom anterior mucosal prolapse had been diagnosed, at one hospital between 1974 and 1976, were reviewed. The commonest symptoms were bleeding (56 per cent), pain (32 per cent) and a sense of prolapse (32 per cent). The prevalence of constipation was significantly higher among women (47 per cent) than men (29 per cent). Perineal descent was present in 20 per cent of cases and was significantly more frequently associated with excessive straining at defaecation (28 per cent) compared with patients in whom there was no history of excessive straining (12 per cent). Sixty-six patients (26 per cent) experienced recurring symptoms over the 10 year period following presentation but did not deteriorate, while 28 patients (11 per cent) deteriorated. Deterioration was associated with a history of symptoms for longer than 1 year at the time of presentation, female sex, and the presence of perineal descent on clinical examination. The risk of developing perineal descent was &amp;lt; 10 per cent over the 5 years after presentation while that of developing sphincter laxity among patients who had already developed perineal descent was 30 per cent over this period. Complete rectal prolapse occurred in 20 per cent (3\/15) of patients with clinical perineal descent and sphincter laxity but was not seen in the absence of these signs. The results of treatment by submucosal phenol injection, mucosal rubber banding, or glycerine suppositories were the same.<\/jats:p>","DOI":"10.1002\/bjs.1800740808","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T10:19:16Z","timestamp":1172917156000},"page":"679-682","source":"Crossref","is-referenced-by-count":31,"title":["Natural history of anterior mucosal prolapse"],"prefix":"10.1093","volume":"74","author":[{"given":"T G","family":"Allen-Mersh","sequence":"first","affiliation":[{"name":"St. Mark's Hospital , London,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M M","family":"Henry","sequence":"additional","affiliation":[{"name":"St. Mark's Hospital , London,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R J","family":"Nicholls","sequence":"additional","affiliation":[{"name":"St. Mark's Hospital , London,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1987,8,1]]},"reference":[{"key":"2024092719462309700_bib1","first-page":"477","article-title":"The syndrome of the descending perineum","volume":"59","author":"Parks","year":"1966","journal-title":"Proc R Soc Med"},{"key":"2024092719462309700_bib2","first-page":"282","volume-title":"Coloproctology and the Pelvic Floor","author":"Rutter","year":"1985"},{"key":"2024092719462309700_bib3","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1136\/jcp.36.11.1264","article-title":"Mucosal prolapse syndrome\u2014a unifying concept for solitary ulcer syndrome and related disorders","volume":"36","author":"DuBoulay","year":"1983","journal-title":"J Clin Pathol"},{"key":"2024092719462309700_bib4","first-page":"398","article-title":"Acute and chronic benign ulcers of the rectum","volume":"153","author":"Duff","year":"1981","journal-title":"Surg Gynecol Obstet"},{"key":"2024092719462309700_bib5","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/bjs.1800720221","article-title":"Electrophysiological and manometric assessment of the pelvic floor in solitary rectal ulcer syndrome","volume":"72","author":"Snooks","year":"1985","journal-title":"Br J Surg"},{"key":"2024092719462309700_bib6","first-page":"718","article-title":"The natural history of benign ulcer of the rectum","volume":"144","author":"Kennedy","year":"1977","journal-title":"Surg Gynecol Obstet"},{"key":"2024092719462309700_bib7","first-page":"129","volume-title":"Statistics in Research","author":"Ostle","year":"1963"},{"key":"2024092719462309700_bib8","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1002\/bjs.1800680409","article-title":"The importance of pain, pruritus and soiling as symptoms of haemorrhoids and their response to haemorrhoidectomy or rubber band ligation","volume":"68","author":"Murie","year":"1981","journal-title":"Br J Surg"},{"key":"2024092719462309700_bib9","volume-title":"Office of Population, Censuses, and Surveys; Welsh Office. 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