{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:01:48Z","timestamp":1781481708157,"version":"3.54.1"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[1987,10,1]],"date-time":"1987-10-01T00:00:00Z","timestamp":560044800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1987,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A survey of six British centres collected data on 83 patients undergoing total pancreatectomy (TP) for chronic pancreatitis between 1977 and 1986. There were 57 men and 26 women with a median age of 38 years (range 19\u201361 years). Half were alcoholics and half had had previous acute pancreatitis. Besides jaundice (14 per cent) severe pain was the indication for the operation; regular opiates had been needed in 82 per cent of patients and 37 per cent were addicted to these drugs. All but 12 had had previous pancreatic or biliary surgery, with a median of two operations and a maximum of six. TP was a one-stage procedure in 32 patients, 42 had had distal resections and 9 proximal resections in the past; the pylorus was preserved in 30. Median operation time was 4 h (range 2\u201318 h) and median blood loss was 3 units (1\u201321 units). Intra-operative complications in 11 patients included haemorrhage in 9. Four deaths occurred within 30 days from bleeding (2), respiratory failure (1) and Roux-loop infarction (1). All but one of the 79 survivors required full pancreatic supplementation and 38 per cent had difficulties in endocrine control. At a median follow-up of 1\u00b75 years (range 0\u00b725\u201310 years), 57 patients (72 per cent) were pain-free and 9 (11 per cent) needed only occasional analgesia. Though 13 (17 per cent) still took regular analgesics, all were symptomatically improved. There have been 10 late deaths (13 per cent), all but one of which are attributable to the operation.<\/jats:p>","DOI":"10.1002\/bjs.1800741013","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T08:41:50Z","timestamp":1172911310000},"page":"912-915","source":"Crossref","is-referenced-by-count":60,"title":["Total pancreatectomy for chronic pancreatitis"],"prefix":"10.1093","volume":"74","author":[{"given":"M J","family":"Cooper","sequence":"first","affiliation":[{"name":"Department of Surgery, Bristol Royal Infirmary ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R C N","family":"Williamson","sequence":"additional","affiliation":[{"name":"Department of Surgery, Bristol Royal Infirmary ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I S","family":"Benjamin","sequence":"additional","affiliation":[{"name":"Hammersmith Hospital ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D C","family":"Carter","sequence":"additional","affiliation":[{"name":"Glasgow Royal Infirmary ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Cuschieri","sequence":"additional","affiliation":[{"name":"Ninewells Hospital , Dundee,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I P","family":"Linehan","sequence":"additional","affiliation":[{"name":"Middlesex Hospital , London,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R C G","family":"Russell","sequence":"additional","affiliation":[{"name":"Middlesex Hospital , London,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H B","family":"Torrance","sequence":"additional","affiliation":[{"name":"Manchester Royal Infirmary ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1987,10,1]]},"reference":[{"key":"2024092719353969600_bib1","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1136\/bmj.2.5909.34","article-title":"Chronic pancreatitis in England: a changing picture?","volume":"2","author":"James","year":"1974","journal-title":"Br Med J"},{"key":"2024092719353969600_bib2","first-page":"318","article-title":"Total pancreatectomy for end-stage chronic pancreatitis","volume":"180","author":"Braasch","year":"1978","journal-title":"Ann Surg"},{"key":"2024092719353969600_bib3","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/BF01658311","article-title":"Results of partial and total pancreaticoduodenectomy in 117 patients with chronic pancreatitis","volume":"5","author":"Gall","year":"1981","journal-title":"World J Surg"},{"key":"2024092719353969600_bib4","first-page":"608","article-title":"Chronic pancreatitis: long-term surgical results of pancreatic duct drainage, pancreatic resection and near-total pancreactectomy and islet autotransplantation","volume":"96","author":"Morrow","year":"1984","journal-title":"Surgery"},{"key":"2024092719353969600_bib5","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1097\/00000658-197909000-00006","article-title":"Surgical treatment of chronic pancreatitis. 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