{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T12:09:28Z","timestamp":1765886968968},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[1987,12,1]],"date-time":"1987-12-01T00:00:00Z","timestamp":565315200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1987,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Although endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic sphincterotomy (ES) have been shown to be valuable in managing patients with acute cholangitis, their role in patients who have simultaneous acute cholangitis and acute pancreatitis is not known. We have reviewed 32 consecutive patients presenting with both conditions over ten years which represents 23\u00b70 per cent of all cases of gallstone-related acute cholangitis and 14\u00b74 per cent of all cases of biliary acute pancreatitis admitted during the same period. The majority of patients were elderly (median 76 years) and female (75 per cent). Five patients had previously undergone cholecystectomy. Eleven patients were clinically shocked (34 per cent) and blood cultures were positive in 9\/14 cases (64 per cent). Twenty patients (63 per cent) had a predicted severe attack of acute pancreatitis (modified Glasgow criteria). Common bile duct (CBD) stones were identified in 15 of 23 patients with successful ERCP. Of these 23 patients, 9 were treated by endoscopic sphincterotomy (ES) alone, 5 by ES and surgery, 4 by surgery alone and 5 were treated conservatively. There was one death (4\u00b73 per cent). Nine patients were managed without cholangiography; four had surgery and five were treated conservatively. There were three deaths (33 percent; P = 0\u00b710). Evidence of recent CBD stone passage was apparent in eight patients (25 per cent) compared with five out of eighty-seven patients (5\u00b77 per cent) with acute cholangitis alone (P&amp;lt;0\u00b705). The results indicate that ERCP and ES may have an important role in the management of these patients.<\/jats:p>","DOI":"10.1002\/bjs.1800741210","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T08:45:25Z","timestamp":1172911525000},"page":"1103-1106","source":"Crossref","is-referenced-by-count":55,"title":["Acute cholangitis in association with acute pancreatitis: Incidence, clinical features and outcome in relation to ERCP and endoscopic sphincterotomy"],"prefix":"10.1093","volume":"74","author":[{"given":"J P","family":"Neoptolemos","sequence":"first","affiliation":[{"name":"Department of Surgery, The Leicester Royal Infirmary , Leicester LE2 7LX,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D L","family":"Carr-Locke","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, The Leicester Royal Infirmary , Leicester LE2 7LX,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Leese","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Leicester Royal Infirmary , Leicester LE2 7LX,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"James","sequence":"additional","affiliation":[{"name":"Department of Radiology, The Leicester Royal Infirmary , Leicester LE2 7LX,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1987,12,1]]},"reference":[{"key":"2024092719362403900_bib1","first-page":"141","article-title":"Acute suppurative cholangitis, a medical and surgical emergency","volume":"54","author":"Andrew","year":"1970","journal-title":"Am J Gastroenterol"},{"key":"2024092719362403900_bib2","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0002-9610(75)90362-1","article-title":"Spectrum of cholangitis","volume":"130","author":"Saik","year":"1975","journal-title":"Am J Surg"},{"key":"2024092719362403900_bib3","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1097\/00000658-198003000-00002","article-title":"Acute cholangitis","volume":"191","author":"Boey","year":"1980","journal-title":"Ann Surg"},{"key":"2024092719362403900_bib4","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/0002-9610(82)90096-4","article-title":"Acute suppurative cholangitis: comparison of internal and external biliary drainage","volume":"143","author":"Lygidakis","year":"1984","journal-title":"Am J Surg"},{"key":"2024092719362403900_bib5","first-page":"369","article-title":"Clinical management of acute cholangitis","volume":"142","author":"Saharia","year":"1976","journal-title":"Surg Gynecol Obstet"},{"key":"2024092719362403900_bib6","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1002\/bjs.1800731214","article-title":"Management of acute cholangitis and the impact of endoscopic sphincterotomy","volume":"73","author":"Leese","year":"1986","journal-title":"Br J Surg"},{"key":"2024092719362403900_bib7","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1097\/00000658-198202000-00003","article-title":"Factors in management of acute cholangitis","volume":"195","author":"Thompson","year":"1982","journal-title":"Ann Surg"},{"key":"2024092719362403900_bib8","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1001\/archsurg.1967.01330100024004","article-title":"Acute suppurative cholangitis","volume":"94","author":"Haupert","year":"1967","journal-title":"Arch Surg"},{"key":"2024092719362403900_bib9","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/0002-9610(69)90286-4","article-title":"Acute obstructive suppurative cholangitis","volume":"117","author":"Hinchey","year":"1969","journal-title":"Am J Surg"},{"key":"2024092719362403900_bib10","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1002\/bjs.1800720718","article-title":"The biliary tract in patients with acute gallstone pancreatitis","volume":"72","author":"Armstrong","year":"1985","journal-title":"Br J Surg"},{"key":"2024092719362403900_bib11","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1056\/NEJM197402282900904","article-title":"Gallstone migration as a cause of acute pancreatitis","volume":"290","author":"Acosta","year":"1974","journal-title":"N Eng J Med"},{"key":"2024092719362403900_bib12","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1097\/00000658-198109000-00008","article-title":"Gallstone pancreatitis: biliary tract pathology in relation to time of operation","volume":"194","author":"Stone","year":"1981","journal-title":"Ann Surg"},{"key":"2024092719362403900_bib13","first-page":"732","article-title":"The role of clinical and biochemical criteria and endoscopic retrograde cholangiopancreatography in the urgent diagnosis of common bile duct stones in acute pancreatitis","volume":"100","author":"Neoptolemos","year":"1986","journal-title":"Surgery"},{"key":"2024092719362403900_bib14","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1136\/gut.26.7.724","article-title":"Acute pancreatitis: a lethal disease of increasing incidence","volume":"26","author":"Corfield","year":"1985","journal-title":"Gut"},{"key":"2024092719362403900_bib15","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1136\/gut.26.2.125","article-title":"Detection of gallstones after acute pancreatitis","volume":"26","author":"Goodman","year":"1985","journal-title":"Gut"},{"key":"2024092719362403900_bib16","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/0009-8981(69)90071-0","article-title":"A new and rapid method for the clinical determination of alpha-amylase activities in human serum and urine","volume":"26","author":"Leska","year":"1969","journal-title":"Clin Chim Acta"},{"key":"2024092719362403900_bib17","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1136\/gut.25.12.1340","article-title":"Prognostic factors in acute pancreatitis","volume":"25","author":"Blamey","year":"1984","journal-title":"Gut"},{"key":"2024092719362403900_bib18","first-page":"447","article-title":"Consequences of preoperative cholangitis and its treatment on the outcome of operation for choledocholithiasis","volume":"94","author":"Pitt","year":"1983","journal-title":"Surgery"},{"key":"2024092719362403900_bib19","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1001\/archsurg.1986.01400060093013","article-title":"A prospective study of ERCP and endoscopic sphincterotomy in the diagnosis and treatment of gallstone acute pancreatitis","volume":"121","author":"Neoptolemos","year":"1986","journal-title":"Arch Surg"},{"key":"2024092719362403900_bib20","first-page":"89","volume-title":"Controversies in Gastroenterology","author":"Pitt","year":"1984"},{"key":"2024092719362403900_bib21","first-page":"424","article-title":"A preliminary report: urgent duodenoscopic sphincterotomy for acute gallstone pancreatitis","volume":"89","author":"Safrany","year":"1981","journal-title":"Surgery"},{"key":"2024092719362403900_bib22","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1097\/00000658-198402000-00005","article-title":"Early or delayed endoscopic papillotomy (EPT) in gallstone pancreatitis","volume":"199","author":"Rosseland","year":"1984","journal-title":"Ann Surg"},{"key":"2024092719362403900_bib23","article-title":"Serial CT scanning in acute pancreatitis (abstract)","volume-title":"Gut","author":"London","year":"1987"},{"key":"2024092719362403900_bib24","first-page":"A648","article-title":"Cholangitis and acute pancreatitis (abstract)","volume":"26","author":"McMahon","year":"1985","journal-title":"Gut"},{"key":"2024092719362403900_bib25","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1056\/NEJM198502143120703","article-title":"Controlled clinical trial of peritoneal lavage for the treatment of severe acute pancreatitis","volume":"312","author":"Mayer","year":"1985","journal-title":"N Engl J Med"}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.1800741210","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/74\/12\/1103\/59382870\/bjs1800741210.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/74\/12\/1103\/59382870\/bjs1800741210.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T19:37:06Z","timestamp":1727465826000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/74\/12\/1103\/6183360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,12,1]]},"references-count":25,"journal-issue":{"issue":"12","published-online":{"date-parts":[[1987,12,1]]},"published-print":{"date-parts":[[1987,12,1]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.1800741210","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"type":"print","value":"0007-1323"},{"type":"electronic","value":"1365-2168"}],"subject":[],"published-other":{"date-parts":[[1987,12]]},"published":{"date-parts":[[1987,12,1]]}}}