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Furthermore, a critical appraisal of the bacteriological data indicated that a certain diagnosis of Meleney's gangrene cannot be provided by the clinical bacteriologist. Finally, the histological features were entirely non-specific thus precluding a definitive diagnosis by the histopathologist. If Meleney's entity cannot be diagnosed its existence becomes debatable. The alternative diagnosis of cutaneous amoebiasis is advanced for consideration. Several of the outstanding features of Meleney's progressive gangrene, hitherto unexplained, are better understood if Entamoeba histolytica is accepted as the prime cause rather than bacteria.<\/jats:p>","DOI":"10.1002\/bjs.1800750327","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T10:52:27Z","timestamp":1172919147000},"page":"267-271","source":"Crossref","is-referenced-by-count":19,"title":["Diagnosis of Meleney's synergistic gangrene"],"prefix":"10.1093","volume":"75","author":[{"given":"J","family":"Davson","sequence":"first","affiliation":[{"name":"Department of Pathology, University of Manchester ,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D M","family":"Jones","sequence":"additional","affiliation":[{"name":"University Hospital of South Manchester , 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