{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:20:21Z","timestamp":1787242821149,"version":"build-2736575974"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[1988,6,1]],"date-time":"1988-06-01T00:00:00Z","timestamp":581126400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1988,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Fasting and postprandial intragastric bile acid concentrations have been estimated and compared in patients with complications of Barrett's oesophagus, patients with Barrett's oesophagus without complications, patients with oesophagitis and a group of normal subjects who acted as controls. There was no significant difference in fasting intragastric bile acid concentrations between the groups. Postprandial bile acid concentrations were significantly greater in the patients with complications of Barrett's than in the remaining groups at 60, 90 and 120 min. Significant concentrations of bile acids were seen in gastric juice of unaltered pH and may be undetected on intra-oesophageal pH monitoring. Duodenogastric reflux may be implicated in the pathogenesis of complications of Barrett's oesophagus.<\/jats:p>","DOI":"10.1002\/bjs.1800750612","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T06:00:24Z","timestamp":1172901624000},"page":"540-543","source":"Crossref","is-referenced-by-count":147,"title":["Implication of duodenogastric reflux in the pathogenesis of Barrett's oesophagus"],"prefix":"10.1093","volume":"75","author":[{"given":"P","family":"Gillen","sequence":"first","affiliation":[{"name":"Department of Surgery, Trinity College Medical School, St. James's Hospital , Dublin 8,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Keeling","sequence":"additional","affiliation":[{"name":"Department of Surgery, Trinity College Medical School, St. James's Hospital , Dublin 8,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P J","family":"Byrne","sequence":"additional","affiliation":[{"name":"Department of Surgery, Trinity College Medical School, St. James's Hospital , Dublin 8,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Healy","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Trinity College Medical School, St. James's Hospital , Dublin 8,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R R","family":"O'Moore","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Trinity College Medical School, St. James's Hospital , Dublin 8,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T P J","family":"Hennessy","sequence":"additional","affiliation":[{"name":"Department of Surgery, Trinity College Medical School, St. James's Hospital , Dublin 8,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1988,6,1]]},"reference":[{"key":"2024092806103769500_bib1","first-page":"29","volume-title":"Barrett's Esophagus: Pathophysiology, Diagnosis and Management","author":"Hamilton","year":"1985"},{"key":"2024092806103769500_bib2","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/S0016-5085(19)35323-5","article-title":"Barrett syndrome: case report and discussion about concepts of pathogenesis","volume":"39","author":"Goldman","year":"1960","journal-title":"Gastroenterology"},{"key":"2024092806103769500_bib3","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/S0016-5085(66)80127-0","article-title":"The columnar-lined esophagus (Barrett syndrome) an acquired condition?","volume":"50","author":"Mossberg","year":"1966","journal-title":"Gastroenterology"},{"key":"2024092806103769500_bib4","first-page":"683","article-title":"The Barrett syndrome (the columnar-lined lower oesophagus): an acquired condition secondary to reflux oesophagitis, a case report with discussion of pathogenesis","volume":"141","author":"Halvorsen","year":"1975","journal-title":"Acta Chir Scand"},{"key":"2024092806103769500_bib5","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/S0016-5085(77)80152-2","article-title":"Regeneration of cardiac type mucosa and acquisition of Barrett mucosa after oesophagogastrostomy","volume":"72","author":"Hamilton","year":"1977","journal-title":"Gastroenterology"},{"key":"2024092806103769500_bib6","first-page":"209","article-title":"Barrett's esophagus: congenital or acquired?: an experimental study of esophageal mucosal regeneration in the dog","volume":"68","author":"Bremner","year":"1970","journal-title":"Surgery"},{"key":"2024092806103769500_bib7","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1001\/archsurg.1983.01390050027005","article-title":"Barrett's esophagus, functional assessment, proposed pathogenesis and surgical therapy","volume":"118","author":"Iascone","year":"1983","journal-title":"Arch Surg"},{"key":"2024092806103769500_bib8","first-page":"A1007","article-title":"Gastro-oesophageal reflux (GOR) in patients with oesophagitis or a columnar lined (Barrett's) oesophagus","volume":"24","author":"Flook","year":"1983","journal-title":"Gut"},{"key":"2024092806103769500_bib9","first-page":"325","article-title":"Twenty-four hour pH monitoring of the distal oesophagus. 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