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It coincided with a significant increase in plasma lactoferrin, evidence of intravascular and intra-alveolar neutrophil elastase release and with arterial hypoxaemia. The postoperative state in these patients had intravascular and pulmonary features often associated with the adult respiratory distress syndrome, and might be a useful model for the study of the early inflammatory events underlying lung injury in man.<\/jats:p>","DOI":"10.1002\/bjs.1800750918","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T11:32:33Z","timestamp":1172921553000},"page":"883-886","source":"Crossref","is-referenced-by-count":30,"title":["Neutrophil degranulation and increased pulmonary capillary permeability following oesophagectomy: A model of early lung injury in man"],"prefix":"10.1093","volume":"75","author":[{"given":"G M","family":"Rocker","sequence":"first","affiliation":[{"name":"Respiratory Medicine Unit, City Hospital , Hucknall Road, Nottingham NG5 1PB,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M S","family":"Wiseman","sequence":"additional","affiliation":[{"name":"Respiratory Medicine Unit, City Hospital , Hucknall Road, Nottingham NG5 1PB,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Pearson","sequence":"additional","affiliation":[{"name":"Department of Medical Physics, City Hospital , Hucknall Road, Nottingham NG5 1PB,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D J","family":"Shale","sequence":"additional","affiliation":[{"name":"Respiratory Medicine Unit, City Hospital , Hucknall Road, Nottingham NG5 1PB,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1988,9,1]]},"reference":[{"key":"2024092806424405900_bib1","first-page":"831","article-title":"Hemodynamic and alveolar protein studies in noncardiac pulmonary edema","volume":"114","author":"Gelb","year":"1976","journal-title":"Am Rev Respir Dis"},{"key":"2024092806424405900_bib2","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1172\/JCI112743","article-title":"Protein permeability in the adult respiratory distress syndrome","volume":"78","author":"Holter","year":"1986","journal-title":"J Clin Invest"},{"key":"2024092806424405900_bib3","first-page":"290","article-title":"Functional and metabolic activity of granulocytes from patients with adult respiratory distress syndrome","volume":"127","author":"Zimmerman","year":"1983","journal-title":"Am Rev Respir Dis"},{"key":"2024092806424405900_bib4","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1164\/arrd.1984.129.5.798","article-title":"Granulocyte-adherence in pulmonary and systemic arterial blood samples from patients with adult respiratory distress syndrome","volume":"89","author":"Zimmerman","year":"1984","journal-title":"Am Rev Respir Dis"},{"key":"2024092806424405900_bib5","first-page":"218","article-title":"Lung neutrophils in the adult respiratory distress syndrome. 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