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Histological examination of the excised fistulae revealed a mixture of columnar, transitional and stratified squamous epithelium lining the tracts in three cases and non-specific connective tissue in the fourth. It is postulated that the presence of these inappropriate types of epithelium (columnar and transitional) along the length of the fistulous tract is evidence of a congenital origin for peri-anal fistulae presenting in the first few months of life.<\/jats:p>","DOI":"10.1002\/bjs.1800750925","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T11:32:33Z","timestamp":1172921553000},"page":"904-905","source":"Crossref","is-referenced-by-count":18,"title":["An aetiology for fistula in ano"],"prefix":"10.1093","volume":"75","author":[{"given":"I K","family":"Pople","sequence":"first","affiliation":[{"name":"Department of Surgery, Norfolk and Norwich Hospital , Brunswick Road, Norwich,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D N L","family":"Ralphs","sequence":"additional","affiliation":[{"name":"Department of Surgery, Norfolk and Norwich Hospital , Brunswick Road, Norwich,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1988,9,1]]},"reference":[{"key":"2024092806240737000_bib1","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1136\/bmj.1.5224.463","article-title":"Pathogenesis and treatment of fistula-in-ano","volume":"1","author":"Parks","year":"1961","journal-title":"Br Med J"},{"key":"2024092806240737000_bib2","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/S0022-3468(85)80399-7","article-title":"Fistula-in-ano in childhood: A congenital etiology","volume":"20","author":"Fitzgerald","year":"1985","journal-title":"J Ped Surg"},{"key":"2024092806240737000_bib3","first-page":"40","article-title":"Anal fistulae in childhood","volume":"26","author":"Duhamel","year":"1975","journal-title":"Am J Proctol"},{"key":"2024092806240737000_bib4","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/BF02553109","article-title":"Ectopic gastric mucosa in duplication of the rectum presenting as a peri-anal fistula","volume":"25","author":"Parkask","year":"1982","journal-title":"Dis Colon Rectum"},{"key":"2024092806240737000_bib5","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/S0022-3468(86)80515-2","article-title":"Normal and abnormal development of the anorectum","volume":"21","author":"Van der Putte","year":"1986","journal-title":"J Ped Surg"},{"key":"2024092806240737000_bib6","first-page":"22","article-title":"Congenital H-type fistulae of the anorectal region","volume":"31","author":"Spitz","year":"1980","journal-title":"Am J Proctol"}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.1800750925","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/75\/9\/904\/59387386\/bjs1800750925.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/75\/9\/904\/59387386\/bjs1800750925.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T06:24:15Z","timestamp":1727504655000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/75\/9\/904\/6182967"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,9,1]]},"references-count":6,"journal-issue":{"issue":"9","published-online":{"date-parts":[[1988,9,1]]},"published-print":{"date-parts":[[1988,9,1]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.1800750925","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"value":"0007-1323","type":"print"},{"value":"1365-2168","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1988,9]]},"published":{"date-parts":[[1988,9,1]]}}}