{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T04:55:42Z","timestamp":1791262542110,"version":"4.1.0"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[1988,10,1]],"date-time":"1988-10-01T00:00:00Z","timestamp":591667200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1988,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The haemostatic effect of two new materials has been compared with surgical gauze and oxidized cellulose using a standardized liver laceration in New Zealand White rabbits. Following excision of a 3 cm2 disc of tissue from the liver, 42 rabbits were randomized to the use of gauze swabs (n = 6), oxidized cellulose (Surgicel\u00ae) (n = 12), porcine collagen (Medistat\u00ae) (n = 12) or calcium alginate (Kaltostat\u00ae) (n = 12) to control the resulting haemorrhage. Blood loss and time to haemostasis were accurately recorded. The absorbable materials were left in situ and animals killed between 2 weeks and 6 months later to examine speed of absorption and resulting adhesions. Calcium alginate stopped bleeding in &amp;lt;3 min in all animals compared with a mean (\u00b1s.e.m.) of 5.7 \u00b1 0.75 min for porcine collagen, 12.5 \u00b1 0.9 min for oxidized cellulose and &amp;gt; 15min with gauze (P &amp;lt; 0.001). Oxidized cellulose and calcium alginate reabsorbed within 3 months leaving a fibrous scar, but a vigorous foreign body reaction was seen with porcine collagen which caused intestinal obstruction in 5 out of 12 animals within 3 months.<\/jats:p>","DOI":"10.1002\/bjs.1800751010","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T10:47:16Z","timestamp":1172918836000},"page":"969-971","source":"Crossref","is-referenced-by-count":61,"title":["Comparison of absorbable materials for surgical haemostasis"],"prefix":"10.1093","volume":"75","author":[{"given":"S D","family":"Blair","sequence":"first","affiliation":[{"name":"Department of Surgery, Charing Cross and Westminster Medical School , London W6,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C M","family":"Backhouse","sequence":"additional","affiliation":[{"name":"Department of Surgery, Charing Cross and Westminster Medical School , London W6,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Harper","sequence":"additional","affiliation":[{"name":"Department of Surgery, Charing Cross and Westminster Medical School , London W6,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Matthews","sequence":"additional","affiliation":[{"name":"Department of Surgery, Charing Cross and Westminster Medical School , London W6,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C N","family":"McCollum","sequence":"additional","affiliation":[{"name":"Department of Surgery, Charing Cross and Westminster Medical School , London W6,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1988,10,1]]},"reference":[{"key":"2024092720012896600_bib1","first-page":"31","article-title":"Some effects of a microcrystalline collagen preparation on 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