{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T06:40:35Z","timestamp":1759992035859},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[1988,11,1]],"date-time":"1988-11-01T00:00:00Z","timestamp":594345600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1988,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Eight patients with faecal incontinence associated with high threshold of rectal sensation are described. All had a normal anal sphincter on clinical and physiological assessment including anal manometry, pudendal nerve latency estimation and single fibre electromyography. In each case however rectal sensation was abnormal. The threshold of rectal sensation was 143 \u00b1 33 ml (range 110\u2013200 ml) compared with control values of 39 \u00b1 14 ml (range 25\u201365 ml) (P &amp;lt; 0.005) in 12 normal age-matched individuals. The degree of rectal distension required to initiate the recto-anal reflex was no different in the incontinent patients (19 ml, range 15\u201325 ml, compared with 22ml, range 15\u201330 ml, in the controls). There was also no difference in the maximal tolerated volume of rectal distension between the groups (291 \u00b1 87 ml and 279 \u00b1 91 ml respectively). These observations may have defined a small group of patients with incontinence in whom an abnormality of rectal sensation rather than sphincter incompetence could be a part of the pathophysiological disorder.<\/jats:p>","DOI":"10.1002\/bjs.1800751112","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T10:37:32Z","timestamp":1172918252000},"page":"1086-1088","source":"Crossref","is-referenced-by-count":51,"title":["Faecal incontinence associated with reduced pelvic sensation"],"prefix":"10.1093","volume":"75","author":[{"given":"D Z","family":"Lubowski","sequence":"first","affiliation":[{"name":"St. Mark's Hospital , City Road, London EC1V 2PS,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R J","family":"Nicholls","sequence":"additional","affiliation":[{"name":"St. Mark's Hospital , City Road, London EC1V 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