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Four patients had received preoperative radiotherapy over a period of 1 week to a total dose of 25\u00b75 Gy and one patient had received postoperative radiotherapy (60 Gy) over a total of 8 weeks. The length of the stenosis varied from 4 to 120 cm. Two patients subsequently underwent reoperation with an abdominoperineal resection and three patients with a Hartmann procedure. In all patients the inferior mesenteric artery had been ligated close to the aorta. It is proposed that the stenosis may have been due to insufficient circulation in the marginal artery. This insufficiency may have been aggravated by the irradiation, as the retained part of the sigmoid colon was partly included in the irradiation target.<\/jats:p>","DOI":"10.1002\/bjs.1800760627","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T13:24:05Z","timestamp":1172928245000},"page":"605-606","source":"Crossref","is-referenced-by-count":23,"title":["Ischaemic strictures in patients treated with a low anterior resection and perioperative radiotherapy for rectal carcinoma"],"prefix":"10.1093","volume":"76","author":[{"given":"L","family":"P\u00e5hlman","sequence":"first","affiliation":[{"name":"Department of Surgery, University Hospital, Akademiska Sjukhuset , S-751 85 Uppsala,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Glimelius","sequence":"additional","affiliation":[{"name":"Department of Oncology, University Hospital, Akademiska Sjukhuset , S-751 85 Uppsala,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Frykholm","sequence":"additional","affiliation":[{"name":"Department of Surgery, University Hospital, Akademiska Sjukhuset , S-751 85 Uppsala,","place":["Sweden"]},{"name":"Department of Oncology, University Hospital, Akademiska Sjukhuset , S-751 85 Uppsala,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1989,6,1]]},"reference":[{"key":"2024092807294976000_bib1","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1002\/bjs.1800691019","article-title":"The mesorectum in rectal cancer surgery\u2014the clue to pelvic recurrence?","volume":"69","author":"Heald","year":"1982","journal-title":"Br J Surg"},{"key":"2024092807294976000_bib2","first-page":"833","article-title":"Long term results of restorative resection and total excision for carcinoma of the middle third of the rectum","volume":"154","author":"McDermott","year":"1982","journal-title":"Surg Gynecol Obstet"},{"key":"2024092807294976000_bib3","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1097\/00000658-198308000-00008","article-title":"The relationship between the extent of distal clearance and survival and local recurrence rates after curative anterior resection for carcinoma of the rectum","volume":"198","author":"Pollett","year":"1983","journal-title":"Ann Surg"},{"key":"2024092807294976000_bib4","doi-asserted-by":"crossref","first-page":"2373","DOI":"10.1002\/1097-0142(19850515)55:10<2373::AID-CNCR2820551012>3.0.CO;2-D","article-title":"Interim analysis of a phase III study on preoperative radiation therapy in resectable rectal carcinoma","volume":"55","author":"Gerard","year":"1985","journal-title":"Cancer"},{"key":"2024092807294976000_bib5","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1002\/1097-0142(19850315)55:6<1182::AID-CNCR2820550607>3.0.CO;2-7","article-title":"Pre-operative short-term radiotherapy in rectal carcinoma. 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