{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T06:33:08Z","timestamp":1759991588923},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[1989,10,1]],"date-time":"1989-10-01T00:00:00Z","timestamp":623203200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1989,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>This retrospective study details the findings and outcome in 34 homosexual men, out of a total of 177 patients, who underwent surgery for non-condylomatous perianal disease over a 2-year period. Of 34 homosexuals 20 presented with anorectal sepsis compared with 11 of 79 heterosexual male patients (\u03c72 = 24.47, P&amp;lt;0.001). Lesions included chronic intersphincteric abscess (eight patients), anal fistula (seven patients) and chronic intersphincteric abscess and fistula (five patients). Anal fissure occurred in 15 patients, anal ulcer in three, skin tags in six, haemorrhoids in two and Kaposi's sarcoma in one. Eight patients were human immunodeficiency virus (HIV) antibody negative, four were asymptomatic HIV antibody positive, 12 had symptomatic HIV infection using the Centers for Disease Control classification and in ten patients HIV status was unknown. Irrespective of the type of surgery performed, healing occurred within 6 weeks of operation in all HIV antibody negative patients, all asymptomatic HIV antibody positive and in only one of nine patients with symptomatic HIV infection. Eight of nine patients with symptomatic HIV infection failed to heal by this time (\u03c72 = 8.98, P&amp;lt;0.05). These findings suggest that the prevalence of anorectal sepsis in homosexual men is high and that symptomatic HIV infection is an important determinant of progress after surgery.<\/jats:p>","DOI":"10.1002\/bjs.1800761026","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T11:07:46Z","timestamp":1172920066000},"page":"1064-1066","source":"Crossref","is-referenced-by-count":39,"title":["Non-condylomatous perianal disease in homosexual men"],"prefix":"10.1093","volume":"76","author":[{"given":"N D","family":"Carr","sequence":"first","affiliation":[{"name":"Departments of Gastroenterology and Genitourinary Medicine, The Middlesex Hospital , Mortimer Street, London W1N 8AA,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Mercey","sequence":"additional","affiliation":[{"name":"Departments of Gastroenterology and Genitourinary Medicine, The Middlesex Hospital , Mortimer Street, London W1N 8AA,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W W","family":"Slack","sequence":"additional","affiliation":[{"name":"Departments of Gastroenterology and Genitourinary Medicine, The Middlesex Hospital , Mortimer Street, London W1N 8AA,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1989,10,1]]},"reference":[{"key":"2024092806221283700_bib1","first-page":"161","volume-title":"Recent Advances in Gastroenterology. 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