{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T13:05:08Z","timestamp":1789909508125,"version":"4.0.1"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[1989,10,1]],"date-time":"1989-10-01T00:00:00Z","timestamp":623203200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1989,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Thirty-seven patients with previously untreated perianal condylomata acuminata were randomly treated by application of 25 per cent podophyllin or scissor excision. The result of treatment was assessed by an independent observer. At 6 weeks, scissor excision completely cleared the warts from 16 of 18 patients (89 per cent) compared with 15 of 19 patients (79 per cent) treated with podophyllin. Following complete clearance by surgery, two patients had recurrent warts at 18 weeks and a further single patient at 42 weeks, giving a cumulative recurrence rate of 19 per cent. In contrast, five of 15 patients whose warts were cleared by podophyllin had recurrent warts at 18 weeks and a further four at 42 weeks representing a cumulative recurrence rate of 60 per cent (\u03c72 = 3.95, d.f. = 1, P = 0.05). At 42 weeks six patients (32 per cent) were free of disease in the podophyllin group compared with 13 (72 per cent) in the scissor excision group (\u03c72 = 4.6, d.f.=1, P = 0.03). Scissor excision is therefore preferable to podophyllin application in the treatment of perianal condylomata acuminata.<\/jats:p>","DOI":"10.1002\/bjs.1800761027","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T11:07:46Z","timestamp":1172920066000},"page":"1067-1068","source":"Crossref","is-referenced-by-count":45,"title":["Podophyllin versus scissor excision in the treatment of perianal condylomata acuminata: A prospective study"],"prefix":"10.1093","volume":"76","author":[{"given":"H T","family":"Khawaja","sequence":"first","affiliation":[{"name":"Department of Surgery, St. Mary's Hospital , Milton Road, Portsmouth PO3 6AD,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1989,10,1]]},"reference":[{"key":"2024092806320685400_bib1","first-page":"190","volume-title":"Papillomaviruses","author":"Gissmann","year":"1986"},{"key":"2024092806320685400_bib2","first-page":"60","volume-title":"On the State of Public Health: Annual Report of the Chief Medical Officer of the Department of Health and Social Security for the year 1978","author":"Department of Health and Social Security","year":"1979"},{"key":"2024092806320685400_bib3","first-page":"81","article-title":"Condyloma acuminatum, 1966\u20131983","volume":"33","year":"1986","journal-title":"MMWR"},{"key":"2024092806320685400_bib4","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1177\/014107687807100305","article-title":"The treatment of perianal and anal condylomata: a new operative technique","volume":"71","author":"Thomson","year":"1978","journal-title":"J R Soc Med"},{"key":"2024092806320685400_bib5","first-page":"208","article-title":"Podophyllin 10% and 25% in the treatment of ano-genital warts: a comparative double-blind study","volume":"57","author":"Simmons","year":"1981","journal-title":"Br J Vener Dis"},{"key":"2024092806320685400_bib6","first-page":"28","volume-title":"Statistics with Confidence","author":"Gardiner","year":"1989"},{"key":"2024092806320685400_bib7","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1001\/jama.1988.03720040062030","article-title":"Interferon and genital warts: much potential, modest progress","volume":"259","author":"Kirby","year":"1988","journal-title":"JAMA"},{"key":"2024092806320685400_bib8","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/0002-9610(62)90531-7","article-title":"Malignant transformation of condyloma acuminatum: review of the literature and report of a case","volume":"103","author":"Siegel","year":"1962","journal-title":"Am J Surg"},{"key":"2024092806320685400_bib9","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/j.1365-2133.1971.tb14199.x","article-title":"Carcinoma in situ associated with virus-containing anal warts","volume":"84","author":"Oriel","year":"1971","journal-title":"Br J Dermatol"},{"key":"2024092806320685400_bib10","first-page":"208","article-title":"5-Fluorouracil in the treatment of penile and urethral condylomata acuminata","volume":"57","author":"Wallin","year":"1981","journal-title":"Br J Vener Dis"},{"key":"2024092806320685400_bib11","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/S0022-5347(17)62412-1","article-title":"Thiotepa in the management of intraurethral condylomata acuminata","volume":"101","author":"Halverstadt","year":"1969","journal-title":"J Urol"},{"key":"2024092806320685400_bib12","first-page":"808","article-title":"The successful treatment of intraurethral condyloma acuminata with colchicine","volume":"105","author":"Gigas","year":"1971","journal-title":"J Urol"},{"key":"2024092806320685400_bib13","first-page":"352","article-title":"Cryosurgery of genital warts","volume":"54","author":"Balsdon","year":"1978","journal-title":"Br J Vener Dis"},{"key":"2024092806320685400_bib14","first-page":"273","article-title":"Cryotherapy versus electrocautery in the treatment of genital warts","volume":"57","author":"Simmons","year":"1981","journal-title":"Br J Vener Dis"},{"key":"2024092806320685400_bib15","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/0002-9378(85)90470-3","article-title":"Improved laser techniques for the elimination of genital and extragenital warts","volume":"153","author":"Baggish","year":"1985","journal-title":"Am J Obstet Gynecol"},{"key":"2024092806320685400_bib16","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1016\/S0140-6736(85)92677-7","article-title":"Comparison of podophyllin application with simple surgical excision in clearance and recurrence of perianal condylomata acuminata","volume":"ii","author":"Jensen","year":"1985","journal-title":"Lancet"},{"key":"2024092806320685400_bib17","first-page":"400","article-title":"Scissor excision of anogenital warts","volume":"58","author":"Gollock","year":"1982","journal-title":"Br J Vener Dis"},{"key":"2024092806320685400_bib18","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1056\/NEJM198610233151704","article-title":"Interferon therapy for condylomata acuminata","volume":"315","author":"Eron","year":"1986","journal-title":"N Engl J Med"},{"key":"2024092806320685400_bib19","doi-asserted-by":"crossref","first-page":"675","DOI":"10.7326\/0003-4819-108-5-675","article-title":"Treatment of condyloma acuminatum with three different interferons administered intralesionally: a double-blind, placebo-controlled trial","volume":"108","author":"Reichman","year":"1988","journal-title":"Ann Intern Med"}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.1800761027","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/76\/10\/1067\/59387632\/bjs1800761027.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/76\/10\/1067\/59387632\/bjs1800761027.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T06:32:15Z","timestamp":1727505135000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/76\/10\/1067\/6172298"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,10,1]]},"references-count":19,"journal-issue":{"issue":"10","published-online":{"date-parts":[[1989,10,1]]},"published-print":{"date-parts":[[1989,10,1]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.1800761027","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"value":"0007-1323","type":"print"},{"value":"1365-2168","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1989,10]]},"published":{"date-parts":[[1989,10,1]]}}}