{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T07:28:04Z","timestamp":1761290884853},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[1990,1,1]],"date-time":"1990-01-01T00:00:00Z","timestamp":631152000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1990,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Exocrine pancreatic function was measured in 14 patients after pancreaticoduodenectomy for periampullary neoplasms in order to assess the patency of a sutureless pancreatico-enteric anastomosis. Pancreatic function was examined by the p-aminobenzoic acid\/p-aminosalicylic acid (PABA\/PAS) test 3\u2013160 months after operation and compared with age- and sex-matched controls. There were no significant differences between mean (s.e.m.) serum PABA concentrations 3 h after ingestion of N-benzoyl-l-tyrosyl-PABA (25\u00b75 (3\u00b76)) \u03bcmol\/l for patients, 26\u00b71 (2\u00b70 (\u03bcmol\/l for controls)). However, the mean (s.e.m.) PABA excretion index was significantly lower in the patients (0\u00b758 (0\u00b708)) than in the controls (0\u00b776 (0\u00b704)). Four patients required pancreatic enzyme supplements for control of diarrhoea. Self-limiting pancreatic leaks occurred in two patients. The results suggest that the sutureless pancreatico-enteric anastomosis has an acceptably low leakage rate but that pancreatic exocrine function is diminished following pancreaticoduodenectomy with this technique. However, the majority of patients require no enzyme supplements and no significant tendency to late stenosis of the anastomosis was demonstrated.<\/jats:p>","DOI":"10.1002\/bjs.1800770129","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T13:30:25Z","timestamp":1172928625000},"page":"83-85","source":"Crossref","is-referenced-by-count":23,"title":["Pancreatic exocrine function after a sutureless pancreaticojejunostomy following pancreaticoduodenectomy"],"prefix":"10.1093","volume":"77","author":[{"given":"R I","family":"Hall","sequence":"first","affiliation":[{"name":"Departments of Surgery and Medicine, St. James's University Hospital , Leeds,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Rhodes","sequence":"additional","affiliation":[{"name":"Freeman Hospital , Newcastle upon Tyne,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L","family":"Isabel-Martinez","sequence":"additional","affiliation":[{"name":"Departments of Surgery and Medicine, St. James's University Hospital , Leeds,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Kelleher","sequence":"additional","affiliation":[{"name":"Departments of Surgery and Medicine, St. James's University Hospital , Leeds,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C W","family":"Venables","sequence":"additional","affiliation":[{"name":"Freeman Hospital , Newcastle upon Tyne,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1990,1,1]]},"reference":[{"key":"2024092807441097800_bib1","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1097\/00000658-193510000-00023","article-title":"Treatment of carcinoma of the ampulla of Vater","volume":"102","author":"Whipple","year":"1935","journal-title":"Ann Surg"},{"key":"2024092807441097800_bib2","first-page":"79","article-title":"Pancreaticoduodenectomy: retrospective review, 1949\u201369","volume":"38","author":"Lansing","year":"1972","journal-title":"Am J Surg"},{"key":"2024092807441097800_bib3","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1001\/archsurg.1966.01320240022005","article-title":"Pancreaticoduodenal cancer","volume":"92","author":"Morris","year":"1966","journal-title":"Arch Surg"},{"key":"2024092807441097800_bib4","first-page":"332","article-title":"Factors influencing morbidity and mortality in pancreaticoduodenectomy","volume":"177","author":"Gilsdorf","year":"1973","journal-title":"Ann Surg"},{"key":"2024092807441097800_bib5","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/0002-9610(86)90024-3","article-title":"Decreased morbidity and mortality after pancreatoduodenectomy","volume":"151","author":"Grace","year":"1986","journal-title":"Am J Surg"},{"key":"2024092807441097800_bib6","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1097\/00000658-198404000-00010","article-title":"Pancreaticoduodenal resection. Surgical experience and evaluation of risk factors in 103 patients","volume":"199","author":"Lerut","year":"1984","journal-title":"Ann Surg"},{"key":"2024092807441097800_bib7","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1136\/gut.28.4.468","article-title":"Improved specificity of the PABA test with p-aminosalicylic acid (PAS)","volume":"28","author":"Hoek","year":"1987","journal-title":"Gut"},{"key":"2024092807441097800_bib8","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1136\/gut.25.5.508","article-title":"Value of serum PABA as a pancreatic function test","volume":"25","author":"Lang","year":"1984","journal-title":"Gut"},{"key":"2024092807441097800_bib9","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1002\/bjs.1800740523","article-title":"New technique for pancreatico-jejunostomy using a biological adhesive","volume":"74","author":"Tashiro","year":"1987","journal-title":"Br J Surg"},{"key":"2024092807441097800_bib10","first-page":"379","article-title":"A secured technique for pancreatojejunal anastomosis in pancreaticoduodenectomy","volume":"163","author":"Manabe","year":"1986","journal-title":"Surg Gynecol Obstet"},{"key":"2024092807441097800_bib11","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/0002-9610(69)90283-9","article-title":"Digestive function after radical pancreaticoduodenectomy","volume":"117","author":"Fish","year":"1969","journal-title":"Am J Surg"},{"key":"2024092807441097800_bib12","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1136\/gut.24.4.318","article-title":"BT-PABA test with plasma PABA measurements: evaluation of sensitivity and specificity","volume":"24","author":"Delchien","year":"1983","journal-title":"Gut"},{"key":"2024092807441097800_bib13","first-page":"200","article-title":"Clinical and experimental study of pancreatic exocrine function after pancreaticoduodenectomy for periampullary carcinoma","volume":"166","author":"Tanaka","year":"1988","journal-title":"Surg Gynecol Obstet"},{"key":"2024092807441097800_bib14","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/BF01655068","article-title":"Residual pancreatic exocrine function before and after pancreaticoduodenectomy for periampullary cancer","volume":"8","author":"Kodama","year":"1984","journal-title":"World J Surg"}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.1800770129","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/77\/1\/83\/59389275\/bjs1800770129.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/77\/1\/83\/59389275\/bjs1800770129.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T07:44:22Z","timestamp":1727509462000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/77\/1\/83\/6172482"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,1,1]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[1990,1,1]]},"published-print":{"date-parts":[[1990,1,1]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.1800770129","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"type":"print","value":"0007-1323"},{"type":"electronic","value":"1365-2168"}],"subject":[],"published-other":{"date-parts":[[1990,1]]},"published":{"date-parts":[[1990,1,1]]}}}