{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T03:32:20Z","timestamp":1785814340549,"version":"3.56.0"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[1990,8,1]],"date-time":"1990-08-01T00:00:00Z","timestamp":649468800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1990,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Fifty infants with infantile hypertrophic pyloric stenosis were studied prospectively to evaluate the reliability of plasma chloride estimation in the assessment of the acid-base status on admission and during correction of alkalaemia. Four cases were subsequently excluded because of a breach of the study protocol, leaving 46 cases in the study. Seventeen (37 per cent) were normoacidaemic on admission; 13 had plasma chloride concentrations of \u2a7e106 mmol\/l and four had chloride concentrations of 100\u2013105 mmol\/l on admission. Twenty-nine (63 per cent) were alkalaemic on admission; six cases had chloride concentrations of 100\u2013105 mmol\/l and 23 cases had concentrations of &amp;lt; 100 mmol\/l. Of those 29 cases requiring correction of alkalaemia, normoacidaemia was achieved at a plasma chloride concentration of \u2a7e 106 mmol\/l in 21 cases (72 per cent) and at a concentration of 100\u2013105 mmol\/l in eight cases (28per cent). Plasma chloride is a reliable parameter in the assessment and correction of alkalaemia in infantile hypertrophic pyloric stenosis provided that a concentration of at least 106 mmol\/l is the goal.<\/jats:p>","DOI":"10.1002\/bjs.1800770827","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T14:44:40Z","timestamp":1172933080000},"page":"922-923","source":"Crossref","is-referenced-by-count":15,"title":["Plasma chloride and alkalaemia in pyloric stenosis"],"prefix":"10.1093","volume":"77","author":[{"given":"D W","family":"Goh","sequence":"first","affiliation":[{"name":"Department of Paediatric Surgery, Birmingham Children's Hospital , Ladywood Middleway, Birmingham B16 BET,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S K","family":"Hall","sequence":"additional","affiliation":[{"name":"Department of Clinical Chemistry, Birmingham Children's Hospital , Ladywood Middleway, Birmingham B16 BET,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Gornall","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, Birmingham Children's Hospital , Ladywood Middleway, Birmingham B16 BET,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R G","family":"Buick","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, Birmingham Children's Hospital , Ladywood Middleway, Birmingham B16 BET,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Green","sequence":"additional","affiliation":[{"name":"Department of Clinical Chemistry, Birmingham Children's Hospital , Ladywood Middleway, Birmingham B16 BET,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J J","family":"Corkery","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, Birmingham Children's Hospital , Ladywood Middleway, Birmingham B16 BET,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1990,8,1]]},"reference":[{"key":"2024092809103194000_bib1","volume-title":"925 Chloride analyser instruction manual"},{"key":"2024092809103194000_bib2","first-page":"550","volume-title":"Practical Clinical Chemistry","author":"Hawks","year":"1988","edition":"6th"},{"key":"2024092809103194000_bib3","first-page":"402","volume-title":"The Body Fluids in Pediatrics","author":"Winters","year":"1973"},{"key":"2024092809103194000_bib4","first-page":"145","volume-title":"Neonatal Anaesthesia and Perioperative Care","author":"Hatch","year":"1986","edition":"2nd"},{"key":"2024092809103194000_bib5","first-page":"839","article-title":"Electrolyte and acid base problems in hypertrophic pyloric stenosis in infancy","volume":"12","author":"Kumar","year":"1975","journal-title":"Ind Pediatr"},{"key":"2024092809103194000_bib6","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1177\/0310057X7300100616","article-title":"Congenital hypertrophic pyloric stenosis - 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