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The importance of the spleen in host defence against malaria and other infections makes splenic preservation desirable whenever possible after rupture of the spleen. Tropical splenomegaly is caused by an abnormal immune response to malaria and is best managed medically. Careful selection of blood donors is essential to prevent transfusion malaria, and routine antimalarial prophylaxis is indicated for blood recipients in many endemic areas. The risk of postoperative malaria may justify chemoprophylaxis in certain patients.<\/jats:p>","DOI":"10.1002\/bjs.1800770905","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T14:53:42Z","timestamp":1172933622000},"page":"964-967","source":"Crossref","is-referenced-by-count":12,"title":["Surgical aspects of malaria"],"prefix":"10.1093","volume":"77","author":[{"given":"E J","family":"Gibney","sequence":"first","affiliation":[{"name":"Department of Surgery, Beaumont Hospital , Dublin 9,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1990,9,1]]},"reference":[{"key":"2024092809011003900_bib1","first-page":"14","article-title":"Changing pattern of antimalarial drug resistance","volume":"82","author":"Peters","year":"1989","journal-title":"J R Soc Med"},{"key":"2024092809011003900_bib2","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/S0140-6736(89)91792-3","article-title":"Plasmodium vivax resistance to chloroquinearticle-title","volume":"ii","author":"Rieckmann","year":"1989","journal-title":"Lancet"},{"key":"2024092809011003900_bib3","first-page":"1395","article-title":"Chloroquine-resistant","volume":"ii","author":"Whitby","year":"1989","journal-title":"Plasmodium vivax. 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