{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:32:14Z","timestamp":1761561134249},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[1991,5,1]],"date-time":"1991-05-01T00:00:00Z","timestamp":673056000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1991,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Perforation of the oesophagus was retrospectively analysed in 59 patients. Cause and extent of perforation, localization, quality of the oesophageal wall and therapeutic modes were subjected to univariate analysis. The perforations of the intrathoracic oesophagus (39) were also subjected to multivariate analysis. Perforation of the cervical oesophagus is seldom lethal and can be adequately treated conservatively in the majority of cases. Perforations of the intrathoracic oesophagus can be divided into two groups, with or without simultaneous perforation of the parietal pleura. The optimal treatment for the group with pleural perforation seems to be resection of the oesophagus and secondary reconstruction, although primary closure is indicated in selected early cases. Perforations of the intrathoracic oesophagus confined to the mediastinum can be adequately treated conservatively in most patients. Perforation of the intra-abdominal oesophagus should be treated like any other intra-abdominal visceral perforation, by closure or diversion, even if this results in resection of the oesophagus.<\/jats:p>","DOI":"10.1002\/bjs.1800780519","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T15:57:54Z","timestamp":1172937474000},"page":"582-585","source":"Crossref","is-referenced-by-count":65,"title":["Treatment of oesophageal perforation: A multivariate analysis"],"prefix":"10.1093","volume":"78","author":[{"given":"H W","family":"Tilanus","sequence":"first","affiliation":[{"name":"Department of Surgery, Erasmus University Hospital \u2018Dijkzigt\u2019 , Rotterdam,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Bossuyt","sequence":"additional","affiliation":[{"name":"Centre for Clinical Decision Analysis, Erasmus University Rotterdam , Rotterdam,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M E","family":"Schattenkerk","sequence":"additional","affiliation":[{"name":"Department of Surgery, Stichting Deventer Ziekenhuizen , Deventer,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Obertop","sequence":"additional","affiliation":[{"name":"Department of Surgery, University Hospital Utrecht , Utrecht,","place":["The Netherlands"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1991,5,1]]},"reference":[{"key":"2024092809463069200_bib1","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1001\/archsurg.1984.01390230084021","article-title":"Esophageal perforations","volume":"119","author":"Ajalat","year":"1984","journal-title":"Arch Surg"},{"key":"2024092809463069200_bib2","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/0002-9610(80)90379-7","article-title":"Management of esophageal perforation","volume":"139","author":"Skinner","year":"1980","journal-title":"Am J Surg"},{"key":"2024092809463069200_bib3","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1111\/j.1445-2197.1987.tb01254.x","article-title":"Oesophageal perforation: a review of 37 cases","volume":"57","author":"Wilde","year":"1987","journal-title":"Aust NZ J Surg"},{"key":"2024092809463069200_bib4","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0003-4975(10)62725-7","article-title":"Diagnosis and recommended management of esophageal perforation and rupture","volume":"42","author":"Bladergroen","year":"1986","journal-title":"Ann Thome Surg"},{"key":"2024092809463069200_bib5","first-page":"134","article-title":"Morbidity and mortality in standard and flexible gastrointestinal endoscopy","volume":"14","author":"Katz","year":"1967","journal-title":"Gastrointest Endosc"},{"key":"2024092809463069200_bib6","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1378\/chest.55.3.184","article-title":"Instrumental perforations of the esophagus","volume":"55","author":"Wychulis","year":"1969","journal-title":"Din Chest"},{"key":"2024092809463069200_bib7","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1136\/bmj.283.6291.583","article-title":"Oesophageal perforation at fibreoptic gastroscopy","volume":"283","author":"Dawson","year":"1981","journal-title":"Br Med J"},{"key":"2024092809463069200_bib8","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1001\/jama.1976.03260350032023","article-title":"Endoscopic complications: results of the 1974 American Society of Gastrointestinal Endoscopy Survey","volume":"235","author":"Silvis","year":"1976","journal-title":"JAMA"},{"key":"2024092809463069200_bib9","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0003-4975(10)61912-1","article-title":"Esophageal perforation","volume":"33","author":"Michel","year":"1982","journal-title":"Ann Thorac Surg"},{"key":"2024092809463069200_bib10","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1097\/00000658-198202000-00011","article-title":"Esophageal perforations after forceful dilatation in achalasia","volume":"195","author":"Slater","year":"1982","journal-title":"Ann Surg"},{"key":"2024092809463069200_bib11","first-page":"355","article-title":"Spontaneous intramural perforation of the esophagus; 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