{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T22:59:08Z","timestamp":1765666748439},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[1991,8,1]],"date-time":"1991-08-01T00:00:00Z","timestamp":681004800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1991,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Current evidence suggests that lower oesophageal sphincter (LOS) competence depends upon both pressure and length. Existing devices can measure length and pressure, but not simultaneously. This methodological problem is a fundamental drawback to understanding LOS function and its role in oesophageal disease. A \u2018sphinctometer\u2019 has been developed, consisting of an oil-filled 3-mm diameter Silastic chamber, 6 cm in length, incorporating a pressure microtransducer designed to provide an integrated pressure reading as a function of length. Its performance has been tested in vitro using human cadaver oesophagus in a specially constructed chamber in which sphincter length and pressure can be varied independently. Comparisons were made with a conventional pull-through technique. Sphinctometer response was linear throughout the LOS pressure range of 0 to 50 mmHg at a fixed LOS length (RS = 0\u00b799; P &amp;lt; 0\u00b7001). Sphinctometer response was also linear at fixed LOS pressure for sphincter lengths from 1 to 6 cm (RS = 0\u00b799; P &amp;lt; 0\u00b7001). This device thus appeared suitable for monitoring function of the human LOS, and has subsequently been successfully incorporated into an ambulatory system for patient use.<\/jats:p>","DOI":"10.1002\/bjs.1800780812","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T16:02:28Z","timestamp":1172937748000},"page":"933-935","source":"Crossref","is-referenced-by-count":31,"title":["The sphinctometer: A new device for measurement of lower oesophageal sphincter function"],"prefix":"10.1093","volume":"78","author":[{"given":"D C","family":"Gotley","sequence":"first","affiliation":[{"name":"University Department of Surgery, Bristol Royal Infirmary , Bristol,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C P","family":"Barham","sequence":"additional","affiliation":[{"name":"University Department of Surgery, Bristol Royal Infirmary , Bristol,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Miller","sequence":"additional","affiliation":[{"name":"University Department of Surgery, Bristol Royal Infirmary , Bristol,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Alderson","sequence":"additional","affiliation":[{"name":"University Department of Surgery, Bristol Royal Infirmary , Bristol,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Arnold","sequence":"additional","affiliation":[{"name":"Gaeltec Ltd , Dunvegan, Isle of Skye,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1991,8,1]]},"reference":[{"key":"2024092809463911000_bib1","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1097\/00000658-197610000-00009","article-title":"Patterns of gastroesophageal reflux in health and disease","volume":"184","author":"DeMeester","year":"1976","journal-title":"Ann Surg"},{"key":"2024092809463911000_bib2","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/0002-9610(79)90008-4","article-title":"Clinical and in vitro analysis of determinants of gastroesophageal competence. A study of the principles of antireflux surgery","volume":"137","author":"DeMeester","year":"1979","journal-title":"Am J Surg"},{"key":"2024092809463911000_bib3","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/0002-9610(86)90007-3","article-title":"Length of the distal esophageal sphincter and competency of the cardia","volume":"151","author":"Bonavina","year":"1986","journal-title":"Am J Surg"},{"key":"2024092809463911000_bib4","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1172\/JCI109667","article-title":"Mechanism of gastroesophageal reflux in recumbent asymptomatic human subjects","volume":"65","author":"Dent","year":"1980","journal-title":"J Clin Invest"},{"key":"2024092809463911000_bib5","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1111\/j.1365-2982.1990.tb00012.x","article-title":"Analysis of spontaneous gastroesophageal reflux and esophageal acid clearance in patients with reflux esophagitis","volume":"2","author":"Dodds","year":"1990","journal-title":"J Gastrointest Motil"},{"key":"2024092809463911000_bib6","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/S0016-5085(72)80142-2","article-title":"Alteration of lower esophageal sphincter characteristics with respiration and proximal esophageal balloon distension","volume":"62","author":"Winans","year":"1972","journal-title":"Gastroenterology"},{"key":"2024092809463911000_bib7","doi-asserted-by":"crossref","first-page":"601","DOI":"10.3109\/00365529009095536","article-title":"The lower esophageal sphincter shown by a computerised representation","volume":"25","author":"Bemelman","year":"1990","journal-title":"Scand J Gastroenterol"}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.1800780812","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/78\/8\/933\/59395160\/bjs1800780812.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/78\/8\/933\/59395160\/bjs1800780812.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T09:46:45Z","timestamp":1727516805000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/78\/8\/933\/6174869"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,8,1]]},"references-count":7,"journal-issue":{"issue":"8","published-online":{"date-parts":[[1991,8,1]]},"published-print":{"date-parts":[[1991,8,1]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.1800780812","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"type":"print","value":"0007-1323"},{"type":"electronic","value":"1365-2168"}],"subject":[],"published-other":{"date-parts":[[1991,8]]},"published":{"date-parts":[[1991,8,1]]}}}