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In contrast, those with large tumours frequently showed little improvement (n = 18) and alternative surgical management was necessary in 12 patients. The overall early mortality rate (&amp;lt; 1 month after first treatment) was 21 per cent. The NdYAG laser offers good palliation and may even cure small colorectal tumours in patients who are unsuitable for surgery. For large circumferential tumours, those associated with obstruction and those close to or involving the anal sphincters, however, the results are poor and better symptom control may be achieved by other means.<\/jats:p>","DOI":"10.1002\/bjs.1800790407","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T16:42:08Z","timestamp":1172940128000},"page":"308-309","source":"Crossref","is-referenced-by-count":8,"title":["Poor palliation of colorectal malignancy with the neodymium yttrium\u2013aluminium\u2013garnet laser"],"prefix":"10.1093","volume":"79","author":[{"given":"N","family":"Bright","sequence":"first","affiliation":[{"name":"Department of Surgery, United Medical and Dental Schools of Guy's Hospital , St Thomas' Street, London SE1 9RT,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Hale","sequence":"additional","affiliation":[{"name":"Department of Surgery, United Medical and Dental Schools of Guy's Hospital , St Thomas' Street, London SE1 9RT,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Mason","sequence":"additional","affiliation":[{"name":"Department of Surgery, United Medical and Dental Schools of Guy's Hospital , St Thomas' Street, London SE1 9RT,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1992,4,1]]},"reference":[{"key":"2024092810345575700_bib1","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1136\/gut.31.7.812","article-title":"Endoscopic Nd:YAG laser treatment of rectosigmoid cancer","volume":"31","author":"Loizou","year":"1990","journal-title":"Gut"},{"key":"2024092810345575700_bib2","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/0016-5085(87)90015-1","article-title":"Palliative treatment of rectosigmoid carcinoma by laser endoscopic photoablation","volume":"92","author":"Brunetaud","year":"1987","journal-title":"Gastroenterology"},{"key":"2024092810345575700_bib3","first-page":"271","article-title":"Laser treatment to rectal malignancies","volume":"6","author":"Houghton","year":"1989","journal-title":"Surg Res Commun"},{"key":"2024092810345575700_bib4","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1007\/BF02553882","article-title":"Use of Nd-YAG laser ablation in colorectal obstruction and palliation in high-risk patients","volume":"32","author":"Walfisch","year":"1989","journal-title":"Dis Colon Rectum"},{"key":"2024092810345575700_bib5","first-page":"710","article-title":"The role of pre-esectional laser recanalization for obstructing carcinomas of the colon and rectum","volume":"106","author":"Eckhauser","year":"1989","journal-title":"Surgery"},{"key":"2024092810345575700_bib6","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/0016-5085(89)90061-9","article-title":"Endoscopic laser treatment for rectosigmoid villous adenoma: factors affecting the results","volume":"97","author":"Brunetaud","year":"1989","journal-title":"Gastroenterology"},{"key":"2024092810345575700_bib7","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/lsm.1900090213","article-title":"Parameters affecting laser palliation in patients with advanced digestive cancers","volume":"9","author":"Brunetaud","year":"1989","journal-title":"Laser Surg Med"}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.1800790407","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/79\/4\/308\/59396874\/bjs1800790407.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/79\/4\/308\/59396874\/bjs1800790407.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T10:35:04Z","timestamp":1727519704000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/79\/4\/308\/6173088"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,4,1]]},"references-count":7,"journal-issue":{"issue":"4","published-online":{"date-parts":[[1992,4,1]]},"published-print":{"date-parts":[[1992,4,1]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.1800790407","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"type":"print","value":"0007-1323"},{"type":"electronic","value":"1365-2168"}],"subject":[],"published-other":{"date-parts":[[1992,4]]},"published":{"date-parts":[[1992,4,1]]}}}