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In a series of 19 patients with necrotizing fasciitis, bacteriological assessment in 15 confirmed the mixed nature of the infection, with Bacteroides sp. isolated from ten patients. All 12 patients who underwent radical surgical excision survived. A subgroup of patients was identified in whom the appearance of necrotizing fasciitis in the abdomen or perineum was indicative of more extensive disease in the retroperitoneal tissues. Surgical resection of all affected tissue was not feasible in these cases and the outcome was uniformly fatal, giving an overall mortality rate for the series of 37 per cent.<\/jats:p>","DOI":"10.1002\/bjs.1800790421","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T16:42:08Z","timestamp":1172940128000},"page":"342-344","source":"Crossref","is-referenced-by-count":43,"title":["Retroperitoneal necrotizing fasciitis"],"prefix":"10.1093","volume":"79","author":[{"given":"MrK R","family":"Woodburn","sequence":"first","affiliation":[{"name":"Division of Surgery, Hairmyres Hospital , Glasgow,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Ramsay","sequence":"additional","affiliation":[{"name":"University Department of Surgery, Western lnfirmary , Glasgow,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Gillespiet","sequence":"additional","affiliation":[{"name":"Division of Surgery, Victoria Infirmary , Glasgow,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D F","family":"Miller","sequence":"additional","affiliation":[{"name":"Division of Surgery, Hairmyres Hospital , Glasgow,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1992,4,1]]},"reference":[{"key":"2024092810420500700_bib1","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1136\/bjo.72.6.428","article-title":"A fatal case of necrotising fasciitis of the eyelid","volume":"72","author":"Walters","year":"1988","journal-title":"Br J Ophthalmol"},{"key":"2024092810420500700_bib2","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/0266-4356(87)90073-8","article-title":"An unusual case of necrotising fasciitis","volume":"25","author":"Steel","year":"1987","journal-title":"Br J Oral Maxillofac Surg"},{"key":"2024092810420500700_bib3","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/0002-9610(81)90353-6","article-title":"Necrotizing fasciitis","volume":"142","author":"Freeman","year":"1981","journal-title":"Am J Surg"},{"key":"2024092810420500700_bib4","first-page":"416","article-title":"Necrotizing fasciitis","volume":"18","author":"Wilson","year":"1952","journal-title":"Am J Surg"},{"key":"2024092810420500700_bib5","first-page":"345","article-title":"Gangrene Foudroyant de la verge","volume":"3","author":"Fournier","year":"1883","journal-title":"Semaine Med"},{"key":"2024092810420500700_bib6","first-page":"765","article-title":"Necrotizing fasciitis: a preventable disaster","volume":"92","author":"Rouse","year":"1982","journal-title":"Surgery"},{"key":"2024092810420500700_bib7","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/0002-9610(77)90283-5","article-title":"Bacteriology of necrotizing fasciitis","volume":"134","author":"Giuliano","year":"1977","journal-title":"Am J Surg"},{"key":"2024092810420500700_bib8","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1001\/archinte.1988.00380030233036","article-title":"Necrotizing fasciitis in adults due to group B streptococcus","volume":"148","author":"Reifler","year":"1988","journal-title":"Arch Intern Med"},{"key":"2024092810420500700_bib9","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1136\/jcp.40.3.335","article-title":"Streptococcal necrotising fasciitis: comparison between histological and clinical features","volume":"40","author":"Barker","year":"1987","journal-title":"J Clin Pathol"},{"key":"2024092810420500700_bib10","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1002\/bjs.1800770309","article-title":"Current hypotheses on synergistic microbial gangrene","volume":"77","author":"Kingston","year":"1990","journal-title":"Br J Surg"},{"key":"2024092810420500700_bib11","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1097\/00000637-198709000-00010","article-title":"Infective cutaneous gangrene: urgency in diagnosis and treatment","volume":"19","author":"Baillie","year":"1987","journal-title":"Ann Plast Surg"},{"key":"2024092810420500700_bib12","first-page":"12","article-title":"Fulminant necrotising fasciitis; 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