{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T12:19:54Z","timestamp":1771676394889,"version":"3.50.1"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[1993,1,1]],"date-time":"1993-01-01T00:00:00Z","timestamp":725846400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1993,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Leg swelling is a significant problem following ankle fracture. Venous pump function and femoral and popliteal venous patency were assessed prospectively in 26 patients with ankle fractures requiring open reduction, internal fixation and immobilization in plaster. Functional venous volume, venous filling index (VFI), ejection volume fraction (EVF) and residual volume fraction (RVF) were measured using air plethysmography at 5 days and at 6, 12 and 18 weeks after fracture. The uninjured leg was used as a control. Popliteal and femoral venous patency was determined using duplex ultrasonography. No patient developed deep vein thrombosis during the study. At 5 days after fracture there was a significant reduction in mean(s.d) EVF, 18\u00b72(12\u00b71) versus 55\u00b79(19\u00b75) percent, and increase in RVF, 87\u00b70(14\u00b73) versus 42\u00b75(22\u00b72) per cent (both P &amp;lt; 0\u00b7001). Analogous values were similar at 6 weeks, EVF 28\u00b75(21\u00b72) versus 55\u00b76(21\u00b79) per cent, RVF 82\u00b72(16\u00b78) versus 48\u00b75(23\u00b78) per cent (both P &amp;lt; 0\u00b7001), and at 12 weeks, EVF 39\u00b71(16\u00b70) versus 60\u00b73(14\u00b79) per cent, RVF 64\u00b77(18\u00b78) versus 38\u00b78(13\u00b72), per cent (both P &amp;lt; 0\u00b7001). However, by 18 weeks there was no significant difference in venous function between fractured and control limbs. It is concluded that there is a significant and prolonged impairment in venous pump function following ankle fracture.<\/jats:p>","DOI":"10.1002\/bjs.1800800112","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T17:23:53Z","timestamp":1172942633000},"page":"36-38","source":"Crossref","is-referenced-by-count":12,"title":["Ankle fracture is associated with prolonged venous dysfunction"],"prefix":"10.1093","volume":"80","author":[{"given":"S","family":"Tierney","sequence":"first","affiliation":[{"name":"Department of Surgery, The Royal College of Surgeons in Ireland, Beaumont Hospital , Dublin 9,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Burke","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Royal College of Surgeons in Ireland, Beaumont Hospital , Dublin 9,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Fitzgerald","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Royal College of Surgeons in Ireland, Beaumont Hospital , Dublin 9,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"O'sullivan","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Royal College of Surgeons in Ireland, Beaumont Hospital , Dublin 9,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Grace","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Royal College of Surgeons in Ireland, Beaumont Hospital , Dublin 9,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Bouchier-Hayes","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Royal College of Surgeons in Ireland, Beaumont Hospital , Dublin 9,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1993,1,1]]},"reference":[{"key":"2024092812002424200_bib1","first-page":"5","volume-title":"Investigation of Patients with Deep Vein Thrombosis and Chronic Venous Insufficiency","author":"Nicolaides","year":"1991"},{"key":"2024092812002424200_bib2","first-page":"209","article-title":"Incidence of thrombosis in patients with tibial fractures","volume":"134","author":"Hjelmstedt","year":"1968","journal-title":"Acta Chirurgica Scandinavica"},{"key":"2024092812002424200_bib3","first-page":"229","article-title":"Phlebographic study of the incidence of thrombosis in the injured and uninjured limb in 55 cases of tibial fracture","volume":"134","author":"Hjelmstedt","year":"1968","journal-title":"Acta Chirurgica Scandinavica"},{"key":"2024092812002424200_bib4","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1002\/bjs.1800781018","article-title":"Impact of duplex scanning on vascular surgical practice","volume":"78","author":"Renton","year":"1991","journal-title":"Br J Surg"},{"key":"2024092812002424200_bib5","first-page":"535","article-title":"Noninvasive diagnosis and quantification of popliteal reflux in the swollen and ulcerated leg","volume":"19","author":"Christopolous","year":"1988","journal-title":"J Cardiovasc Surg (Torino)"},{"key":"2024092812002424200_bib6","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/0741-5214(87)90205-9","article-title":"Air plethysmography and the effect of elastic compression on venous haemodynamics of the leg","volume":"5","author":"Christopolous","year":"1987","journal-title":"J Vasc Surg"},{"key":"2024092812002424200_bib7","first-page":"23","article-title":"Air plethysmography (APG). A new technique to evaluate patients with chronic venous insufficiency","volume":"15","author":"Katz","year":"1991","journal-title":"Journal of Vascular Technology"},{"key":"2024092812002424200_bib8","first-page":"829","article-title":"Pathogenesis of venous ulceration in relation to the calf muscle pump","volume":"106","author":"Christopolous","year":"1989","journal-title":"Surgery"},{"key":"2024092812002424200_bib9","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1302\/0301-620X.69B5.3680341","article-title":"The postphlebitic syndrome following shaft fractures of the leg","volume":"69-B","author":"Aitken","year":"1987","journal-title":"J Bone Joint Surg [Br]"},{"key":"2024092812002424200_bib10","doi-asserted-by":"crossref","first-page":"110","DOI":"10.3109\/17453678508994331","article-title":"Venous function after fracture of the lower extremity; a nine year follow-up of 150 patients","volume":"56","author":"Lindhagen","year":"1985","journal-title":"Acta Orthop Scand"},{"key":"2024092812002424200_bib11","doi-asserted-by":"crossref","first-page":"149","DOI":"10.3109\/17453678208992193","article-title":"Venous insufficiency as a late complication of tibial fracture","volume":"53","author":"Willen","year":"1982","journal-title":"Acta Orthop Scand"},{"key":"2024092812002424200_bib12","first-page":"29","article-title":"Venous imaging of the extremities: our first twenty-five hundred cases","volume":"10","author":"Hannan","year":"1986","journal-title":"Bruit"},{"key":"2024092812002424200_bib13","first-page":"187","article-title":"Characterisation of lower extremity venous disease using real time B-mode ultrasonic imaging","volume":"11","author":"Semrow","year":"1987","journal-title":"Journal of Vascular Technology"},{"key":"2024092812002424200_bib14","first-page":"109","article-title":"The venous pump of the human foot - preliminary report","volume":"98","author":"Gardener","year":"1983","journal-title":"Bristol Medicochirurgical Journal"},{"key":"2024092812002424200_bib15","first-page":"2000","volume-title":"Rockwood and Green's Fractures in Adults","author":"Van der Griend","year":"1991"},{"key":"2024092812002424200_bib16","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1302\/0301-620X.72B5.2211762","article-title":"Reduction of posttraumatic swelling and compartment pressure by impulse compression of the foot","volume":"72-B","author":"Gardener","year":"1991","journal-title":"J Bone Joint Surg [Br]"}],"container-title":["Journal of British Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbjs.1800800112","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/80\/1\/36\/59399449\/bjs1800800112.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjs\/article-pdf\/80\/1\/36\/59399449\/bjs1800800112.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T12:00:30Z","timestamp":1727524830000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjs\/article\/80\/1\/36\/6175383"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,1,1]]},"references-count":16,"journal-issue":{"issue":"1","published-online":{"date-parts":[[1993,1,1]]},"published-print":{"date-parts":[[1993,1,1]]}},"URL":"https:\/\/doi.org\/10.1002\/bjs.1800800112","relation":{},"ISSN":["0007-1323","1365-2168"],"issn-type":[{"value":"0007-1323","type":"print"},{"value":"1365-2168","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1993,1]]},"published":{"date-parts":[[1993,1,1]]}}}