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This study attempted to determine whether axillary node status could be accurately predicted using selected criteria in women with screen-detected breast cancer. Of 223 breast cancers excised in the Greater Manchester breast screening programme, 180 were invasive and 40 of these had associated lymph node metastases. The presence of involved nodes was associated with large tumour size, high tumour grade and the absence of mammographic microcalcification. Multiple logistic regression analysis revealed that each of these three factors was independently significant. Women with a screen-detected breast cancer &amp;lt; 1 cm in diameter or those with grade I tumours &amp;lt;3 cm (35 per cent of the total) could be spared axillary surgery with an expected reduction in morbidity and operating time.<\/jats:p>","DOI":"10.1002\/bjs.1800800409","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T17:49:19Z","timestamp":1172944159000},"page":"436-438","source":"Crossref","is-referenced-by-count":44,"title":["Treatment of the axilla in patients with screen-detected breast cancer"],"prefix":"10.1093","volume":"80","author":[{"given":"J","family":"Walls","sequence":"first","affiliation":[{"name":"Department of Surgery, University Hospital of South Manchester , Manchester,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C R M","family":"Boggis","sequence":"additional","affiliation":[{"name":"Department of Radiology, University Hospital of South Manchester , Manchester,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Wilson","sequence":"additional","affiliation":[{"name":"Department of Radiology, University Hospital of South Manchester , Manchester,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D L","family":"Asbury","sequence":"additional","affiliation":[{"name":"Department of Radiology, University Hospital of South Manchester , Manchester,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J V","family":"Roberts","sequence":"additional","affiliation":[{"name":"Department of Surgery, University Hospital of South Manchester , Manchester,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N J","family":"Bundred","sequence":"additional","affiliation":[{"name":"Department of Surgery, University Hospital of South Manchester , Manchester,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R E","family":"Mansel","sequence":"additional","affiliation":[{"name":"Department of Surgery, University Hospital of South Manchester , Manchester,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1993,4,1]]},"reference":[{"key":"2024092812561838900_bib1","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/0140-6736(91)92172-X","article-title":"The axilla: not a no-go zone","volume":"337","author":"Fentiman","year":"1991","journal-title":"Lancet"},{"key":"2024092812561838900_bib2","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1002\/bjs.1800720512","article-title":"The efficacy of lower axillary sampling in obtaining lymph node status in brest cancer: a controlled randomized trial","volume":"72","author":"Steele","year":"1985","journal-title":"Br J Surg"},{"key":"2024092812561838900_bib3","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1001\/archsurg.1991.01410350026004","article-title":"Total axillary lymphadenectomy in the management of breast cancer","volume":"126","author":"Senofsky","year":"1991","journal-title":"Arch Surg"},{"key":"2024092812561838900_bib4","first-page":"267","article-title":"The effect of surgical technique on local recurrence rates following mastectomy","volume":"12","author":"Benson","year":"1986","journal-title":"Eur J Surg Oncol"},{"key":"2024092812561838900_bib5","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1136\/bmj.302.6773.360","article-title":"Axillary dissection in primary breast cancer","volume":"302","author":"O'Dwyer","year":"1991","journal-title":"BMJ"},{"key":"2024092812561838900_bib6","first-page":"407","article-title":"Breast cancer: risk of axillary recurrence in node negative patients following partial dissection of the axilla","volume":"14","author":"Graversen","year":"1988","journal-title":"Eur J Surg Oncol"},{"key":"2024092812561838900_bib7","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1038\/bjc.1957.43","article-title":"Histological grading and prognosis in breast cancer. 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