{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:47:09Z","timestamp":1759333629006},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[1993,8,1]],"date-time":"1993-08-01T00:00:00Z","timestamp":744163200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1993,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A total of 91 patients with melanoma of the head and neck treated between 1973 and 1991 were studied prospectively with regard to prognostic features, treatment and outcome. Other than Breslow thickness, the only important prognostic feature was the less aggressive nature of lentigo maligna melanoma. A policy of selective excision margins, 1 cm for impalpable and 2 cm for palpable lesions, was found to be safe, although preliminary biopsy should be used if there is diagnostic uncertainty or where the expected extent of surgery entails a mutilating procedure. Local recurrence rates were not affected by the method of wound closure, which should be determined by the best functional and cosmetic outcome. These results support the trend against prophylactic neck dissection. Such dissection, when indicated for lesions of the face, pinna, anterior scalp and parotid area, should routinely include superficial parotidectomy. Uncontrolled symptomatic locoregional recurrence is an uncommon complication that may occur despite radical primary surgery. The role of preoperative radiotherapy for high-risk melanoma in this situation warrants investigation.<\/jats:p>","DOI":"10.1002\/bjs.1800800821","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T19:27:00Z","timestamp":1172950020000},"page":"998-1000","source":"Crossref","is-referenced-by-count":11,"title":["Management of malignant melanoma of the head and neck"],"prefix":"10.1093","volume":"80","author":[{"given":"D J A","family":"Orr","sequence":"first","affiliation":[{"name":"Department of Surgery, University of Wales College of Medicine , Heath Park, Cardiff CF4 4XN,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L E","family":"Hughes","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Wales College of Medicine , Heath Park, Cardiff CF4 4XN,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Horgan","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Wales College of Medicine , Heath Park, Cardiff CF4 4XN,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1993,8,1]]},"reference":[{"key":"2024092812215384200_bib1","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1111\/j.1365-2230.1990.tb02132.x","article-title":"Malignant melanoma in West Glamorgan \u2013 increasing incidence and improving prognosis, 1986\u201388","volume":"15","author":"Roberts","year":"1990","journal-title":"Clin Exp Dermatol"},{"key":"2024092812215384200_bib2","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1002\/1097-0142(19831101)52:9<1748::AID-CNCR2820520932>3.0.CO;2-B","article-title":"Changing trends in cutaneous melanoma over a quarter of a century in Alabama, USA, and New South Wales, Australia","volume":"52","author":"Balch","year":"1983","journal-title":"Cancer"},{"key":"2024092812215384200_bib3","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/S0140-6736(85)90126-6","article-title":"Malignant melanoma in Scotland 1979\u20131983","volume":"ii","author":"MacKie","year":"1985","journal-title":"Lancet"},{"key":"2024092812215384200_bib4","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1097\/00000658-197011000-00017","article-title":"Thickness, cross-sectional areas and depth of invasion in the prognosis of cutaneous melanoma","volume":"172","author":"Breslow","year":"1970","journal-title":"Ann Surg"},{"key":"2024092812215384200_bib5","first-page":"705","article-title":"The histogenesis and biologic behavior of primary human malignant melanomas of the skin","volume":"29","author":"Clark","year":"1969","journal-title":"Cancer Res"},{"key":"2024092812215384200_bib6","first-page":"7","article-title":"A policy of selective excision for primary cutaneous malignant melanoma","volume":"11","author":"Taylor","year":"1985","journal-title":"Eur J Surg Oncol"},{"key":"2024092812215384200_bib7","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1288\/00005537-198908000-00010","article-title":"Cutaneous malignant melanoma of the head and neck","volume":"99","author":"Fisher","year":"1989","journal-title":"Laryngoscope"},{"key":"2024092812215384200_bib8","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/0002-9610(91)90138-4","article-title":"Experience with 998 cutaneous melanomas of the head and neck over 30 years","volume":"162","author":"O'Brien","year":"1991","journal-title":"Am J Surg"},{"key":"2024092812215384200_bib9","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1097\/00000658-198412000-00017","article-title":"Head and neck melanoma in 534 clinical stage I patients: a prognostic factors analysis and results of surgical treatment","volume":"200","author":"Urist","year":"1984","journal-title":"Ann Surg"},{"key":"2024092812215384200_bib10","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1002\/1097-0142(19880815)62:4<831::AID-CNCR2820620432>3.0.CO;2-X","article-title":"Prognostic factors in head and neck melanoma: effect of lesion location","volume":"62","author":"Wanebo","year":"1988","journal-title":"Cancer"},{"key":"2024092812215384200_bib11","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/S0046-8177(83)80298-6","article-title":"How wide and deep is wide and deep enough? 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