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Two groups of patients were analysed: the first (n = 137) had tumour submitted to stereotactic biopsy; the second (n = 60) had malignant glioma operated on by craniotomy and tumour resection. All three staging parameters signficantly influenced survival. Histopathological grade was the most significant factor, and the only independent variable on multivariate analysis, followed by extent of tumour and then extent of surgical resection. The data support the applicability of the proposed parameters for a staging classfication of hemispheric brain glioma.<\/jats:p>","DOI":"10.1002\/bjs.1800800920","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T19:33:19Z","timestamp":1172950399000},"page":"1130-1133","source":"Crossref","is-referenced-by-count":12,"title":["Staging of supratentorial hemispheric glioma using tumour extension, histopathological grade and extent of surgical resection"],"prefix":"10.1093","volume":"80","author":[{"given":"M","family":"Iacoangeli","sequence":"first","affiliation":[{"name":"Institute of Neurosurgery, Catholic University School of Medicine , Rome,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Roselli","sequence":"additional","affiliation":[{"name":"Institute of Neurosurgery, Catholic University School of Medicine , Rome,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Prezioso","sequence":"additional","affiliation":[{"name":"Institute of Neurosurgery, Catholic University School of Medicine , Rome,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Scerrat","sequence":"additional","affiliation":[{"name":"Institute of Neurosurgery, Catholic University School of Medicine , Rome,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G F","family":"Rossi","sequence":"additional","affiliation":[{"name":"Institute of Neurosurgery, Catholic University School of Medicine , Rome,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1993,9,1]]},"reference":[{"key":"2024092812563502600_bib1","first-page":"6","volume-title":"Manual for Staging of Cancer","author":"Beahrs","year":"1988","edition":"3rd"},{"key":"2024092812563502600_bib2","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/978-3-642-82982-6","volume-title":"TNM Classification of Malignant Tumours","author":"Hermanek","year":"1987"},{"key":"2024092812563502600_bib3","first-page":"946","article-title":"Spread of malignant gliomas","volume":"66","author":"Choucair","year":"1987","journal-title":"J Neurosurg"},{"key":"2024092812563502600_bib4","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1016\/0360-3016(89)90941-3","article-title":"Patterns of failure following treatment for glioblastoma multiforme and anaplastic astrocytoma","volume":"16","author":"Wallner","year":"1989","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2024092812563502600_bib5","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1002\/1097-0142(19871001)60:7<1519::AID-CNCR2820600719>3.0.CO;2-1","article-title":"The incidence of multifocal cerebral gliomas. 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