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Within 6 h of endarterectomy, median MCAV in the operated hemisphere was 48 per cent (95 per cent confidence interval 37\u201360 per cent) above that on admission and remained 27 per cent (95 per cent confidence interval 19\u201337 per cent) higher at 72h. There was a similar, but less marked, increase in MCAV in the contralateral middle cerebral artery during the same time period. There was no association between the postoperative increase in MCAV and clinical presentation, admission MCAV, the presence or absence of a residual neurological deficit or infarction on computed tomography before operation, carotid clamp time, shunt usage, internal carotid artery stump pressure or MCAV during clamping. The greatest increase in MCAV was observed in patients with internal carotid artery stenosis \u2a7e 50 per cent and, more particularly, in those with preoperative evidence of impaired cerebrovascular reserve. In the latter patients, MCAV was 100 per cent above the admission level within 12 h of operation and was still 50 per cent raised at 72 h.<\/jats:p>","DOI":"10.1002\/bjs.1800801209","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T17:34:17Z","timestamp":1172943257000},"page":"1523-1527","source":"Crossref","is-referenced-by-count":27,"title":["Factors influencing the hyperaemic response after carotid endarterectomy"],"prefix":"10.1093","volume":"80","author":[{"given":"A R","family":"Naylor","sequence":"first","affiliation":[{"name":"Department of Vascular Surgery, The Royal Infirmary and Western General Hospital , Edinburgh,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M R","family":"Whyman","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, The Royal Infirmary and Western General Hospital , Edinburgh,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J A W","family":"Wildsmith","sequence":"additional","affiliation":[{"name":"Department of Anaesthetics, The Royal Infirmary and Western General Hospital , Edinburgh,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J H","family":"McClure","sequence":"additional","affiliation":[{"name":"Department of Anaesthetics, The Royal Infirmary and Western General Hospital , Edinburgh,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"McL. 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