{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:39:41Z","timestamp":1773103181855,"version":"3.50.1"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[1993,12,1]],"date-time":"1993-12-01T00:00:00Z","timestamp":754704000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1993,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A randomized controlled trial was performed to evaluate patch angioplasty for patients undergoing carotid endarterectomy. There were 213 patient episodes affecting 148 men and 65 women, with 109 allocated to patch angioplasty. Following surgery six patients suffered transient ischaemic attacks but these did not delay discharge from hospital. Six individuals (four patched operations, two not patched) required re-exploration for postoperative haemorrhage and eight (two patched procedures, six not) had potentially serious neurological problems after operation. Of these eight patients, four (none receiving patch angioplasty) underwent re-exploration and in each case a clot was removed and a patch inserted; three of the four made a good long-term recovery. The other four patients suffered completed strokes from which one died. Two further patients (one patched procedure, one not) died after operation from myocardial events, giving an overall 30-day stroke or mortality rate of 2\u00b78 per cent. Objective follow-up assessment with duplex scanning at 1 year was completed by 94\u00b78 per cent of patients; significantly more vessel restenoses and occlusions were observed in those not receiving patches (P &amp;lt; 0\u00b701). Patch angioplasty reduces the number of immediate postoperative complications, and significantly lowers vessel restenosis and occlusion rates at 1 year after operation.<\/jats:p>","DOI":"10.1002\/bjs.1800801211","type":"journal-article","created":{"date-parts":[[2007,3,3]],"date-time":"2007-03-03T17:34:17Z","timestamp":1172943257000},"page":"1528-1530","source":"Crossref","is-referenced-by-count":69,"title":["Randomized controlled trial of patch angioplasty for carotid endarterectomy"],"prefix":"10.1093","volume":"80","author":[{"given":"C J","family":"Ranaboldo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A A B Barros","family":"D'sa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P R F","family":"Bell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A D B","family":"Chant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P M","family":"Perry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1993,12,1]]},"reference":[{"key":"2024092811413350100_bib1","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1016\/0140-6736(91)92916-P","article-title":"MRC European Carotid Surgery Trial: interim results for symptomatic patients with severe (70\u201399%) or with mild (0\u201329%) carotid stenosis","volume":"337","author":"European Carotid Surgery Trialists' Collaborative Group","year":"1991","journal-title":"Lancet"},{"key":"2024092811413350100_bib2","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1056\/NEJM199108153250701","article-title":"Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis","volume":"325","author":"North American Symptomatic Carotid Endarterectomy Trial Collaborators","year":"1991","journal-title":"N Engl J Med"},{"key":"2024092811413350100_bib3","first-page":"47","volume-title":"The Health of the Nation","author":"Department of Health","year":"1992"},{"key":"2024092811413350100_bib4","doi-asserted-by":"crossref","first-page":"743","DOI":"10.3171\/jns.1984.61.4.0743","article-title":"Saphenous vein patch grafts in carotid endarterectomy","volume":"61","author":"Little","year":"1984","journal-title":"J Neurosurg"},{"key":"2024092811413350100_bib5","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1161\/01.STR.15.6.972","article-title":"The rationale for patch-graft angioplasty after carotid endarterectomy: early and long-term follow-up","volume":"15","author":"Deriu","year":"1984","journal-title":"Stroke"},{"key":"2024092811413350100_bib6","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/0741-5214(89)90040-2","article-title":"Vein patch versus primary closure for carotid endarterectomy. 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